Evidence map›Paper›PMID 30276224›Full record

ArticleCurrent opinion in behavioral sciences2018

The Role of Learning in Threat Imminence and Defensive Behaviors.

Michael S Fanselow

Abstract read
In one paragraph

Article in Current opinion in behavioral sciences, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 55 papers.

0numbers the graph read from it
0cells of the map it votes in
55citing papers in PubMed
3.3field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

55 citing papers in PubMed, 93 citations in OpenAlex.

  1. Article
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  5. Imagery-based fear conditioning enhances the late positive potential.Cognitive, affective & behavioral neuroscience · 2026
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  19. The neurobiology of interoception and affect.Trends in cognitive sciences · 2024
    Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

1 author at 1 institution in 1 country.

Michael S FanselowStaglin Center for Brain and Behavioral Health, Department of Psychology, Department of Psychiatry and Biobehavioral Sciences, University of California, Los Angeles, Los Angeles, CA 90095 USA.
University of California, Los Angeles · US

Funding

Contextual Fear Differentiation, Sex Differences and AcetylcholineR01MH062122 · NIMH · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI FANSELOW, MICHAEL S · 2001 to 2021
$7.3M
NIMH NIH HHS R01 MH062122
6 · The paper itself

Abstract

Life threatening situations as urgent as defending against a predator precludes the use of slow trial and error strategies. Natural selection has led to the evolution of a behavioral system that has 3 critical elements. 1) When it is activated it limits the behaviors available to the organism to a set of prewired responses that have proven over phylogeny to be effective at defense. 2) A rapid learning system, called Pavlovian fear conditioning, that has the ability to immediately identify threats and promote prewired defensive behaviors. 3) That learning system has the ability to integrate several informational dimensions to determine threat imminence and this allows the organism to match the most effective defensive behavior to the current situation. The adaptive significance of conscious experiential states is also considered.

Indexed as

amygdalaAnxietyavoidanceconsciousnessDefensive BehaviorFearFear ConditioningfreezingInnate FearPanicPredatory Imminenceselective associationThreat Imminence

Identifiers

PMID30276224
PMCPMC6162067
OpenAlexW2805962577

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.