Evidence map›Paper›PMID 30276213›Full record

ArticleBioMed research international2018

MultiParametric Magnetic Resonance Imaging-Based Nomogram for Predicting Prostate Cancer and Clinically Significant Prostate Cancer in Men Undergoing Repeat Prostate Biopsy.

Cong Huang, Gang Song, He Wang, Guangjie Ji, Jie Li, Yuke Chen, Yu Fan, Dong Fang, Gengyan Xiong, Zhongcheng Xin and 1 more

Abstract read
In one paragraph

Article in BioMed research international, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Review
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Cong HuangDepartment of Urology, Peking University First Hospital, Beijing 100034, China.ORCID 0000-0002-1609-1635
Gang SongDepartment of Urology, Peking University First Hospital, Beijing 100034, China.ORCID 0000-0003-2176-5419
He WangDepartment of Radiology, Peking University First Hospital, Beijing 100034, China.
Guangjie JiDepartment of Urology, Peking University First Hospital, Beijing 100034, China.
Jie LiDepartment of Urology, Lishui Central Hospital, The Fifth Affiliated Hospital, Wenzhou Medical University, Lishui, 323000, Zhejiang, China.
Yuke ChenDepartment of Urology, Peking University First Hospital, Beijing 100034, China.
Yu FanDepartment of Urology, Peking University First Hospital, Beijing 100034, China.
Dong FangInstitute of Urology, Peking University, National Urological Cancer Center of China, Beijing 100034, China.
Gengyan XiongDepartment of Urology, Peking University First Hospital, Beijing 100034, China.ORCID 0000-0003-1385-5297
Zhongcheng XinInstitute of Urology, Peking University, National Urological Cancer Center of China, Beijing 100034, China.
Liqun ZhouDepartment of Urology, Peking University First Hospital, Beijing 100034, China.ORCID 0000-0003-2795-9038

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveTo develop and internally validate nomograms based on multiparametric magnetic resonance imaging (mpMRI) to predict prostate cancer (PCa) and clinically significant prostate cancer (csPCa) in patients with a previous negative prostate biopsy. MATERIALS AND

methodsThe clinicopathological parameters of 231 patients who underwent a repeat systematic prostate biopsy and mpMRI were reviewed. Based on Prostate Imaging and Reporting Data System, the mpMRI results were assigned into three groups: Groups "negative," "suspicious," and "positive." Two clinical nomograms for predicting the probabilities of PCa and csPCa were constructed. The performances of nomograms were assessed using area under the receiver operating characteristic curves (AUCs), calibrations, and decision curve analysis.

resultsThe median PSA was 15.03 ng/ml and abnormal DRE was presented in 14.3% of patients in the entire cohort. PCa was detected in 75 patients (32.5%), and 59 (25.5%) were diagnosed with csPCa. In multivariate analysis, age, prostate-specific antigen (PSA), prostate volume (PV), digital rectal examination (DRE), and mpMRI finding were significantly independent predictors for PCa and csPCa (all

conclusionmpMRI combined with age, PSA, PV, and DRE can help predict the probability of PCa and csPCa in patients who underwent a repeat systematic prostate biopsy after a previous negative biopsy. The two nomograms may aid the decision-making process in men with prior benign histology before the performance of repeat prostate biopsy.

Indexed as

NomogramsAgedBiopsyHumansMagnetic Resonance ImagingMaleMiddle AgedProstate-Specific AntigenProstatic NeoplasmsRetrospective StudiesTransurethral Resection of ProstateProstate-Specific Antigen

Identifiers

PMID30276213
PMCPMC6157114

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.