ArticlePlastic and reconstructive surgery. Global open2018
Efficacy and Safety of Intravenous Meloxicam in Subjects with Moderate-to-severe Pain Following Abdominoplasty.
Article in Plastic and reconstructive surgery. Global open, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
16 citing papers in PubMed, 32 citations in OpenAlex.
- HSK21542 in patients with postoperative pain: two phase 3, multicentre, double-blind, randomized, controlled trials.Nature communications · 2025Trial
- A randomized, double-blind, placebo-controlled study to evaluate the efficacy and safety of a bupivacaine hydrochloride implant in patients undergoing abdominoplasty.Regional anesthesia and pain medicine · 2023Trial
- Safety and Efficacy of Perioperative Intravenous Meloxicam for Moderate-to-Severe Pain Management in Total Knee Arthroplasty: A Randomized Clinical Trial.Pain medicine (Malden, Mass.) · 2021Trial
- Preemptive meloxicam achieves a better effect on postoperative pain control and similar tolerance compared with postoperative meloxicam in patients receiving arthroscopic knee surgery.Inflammopharmacology · 2019Trial
- A Phase 3, Randomized, Placebo-Controlled Evaluation of the Safety of Intravenous Meloxicam Following Major Surgery.Clinical pharmacology in drug development · 2019Trial
- Trial
- Applications of micro/nano drug delivery systems in cancer pain management.Bioactive materials · 2026Review
- Innovations in Pain Management for Abdominoplasty Patients: A Systematic Review.Journal of personalized medicine · 2024Review
- A Phase I Study to Evaluate the Safety, Tolerability, and Pharmacokinetics of Novel Intravenous Formulation of Meloxicam (QP001) in Healthy Chinese Subjects.Drug design, development and therapy · 2023Article
- Budget Impact and Cost-Effectiveness of Intravenous Meloxicam to Treat Moderate-Severe Postoperative Pain.Advances in therapy · 2022Article
- Optimizing Nonopioid Analgesia and Different Pain Management Options following Abdominoplasty: A Systematic Literature Review.Plastic and reconstructive surgery. Global open · 2022Article
- Efficacy and Safety of Intravenously Administered Tramadol in Patients with Moderate to Severe Pain Following Bunionectomy: A Randomized, Double-Blind, Placebo-Controlled, Dose-Finding Study.Pain and therapy · 2020Article
- Efficacy of non-opioid analgesics to control postoperative pain: a network meta-analysis.BMC anesthesiology · 2020Article
- Platelet Function: Meloxicam Intravenous in Whole Blood Samples From Healthy Volunteers.Clinical pharmacology in drug development · 2020Article
- Safety, Tolerability, and Effect on Opioid Use of Meloxicam IV Following Orthopedic Surgery.Journal of pain research · 2020Article
- Meloxicam in the management of post-operative pain: Narrative review.Journal of anaesthesiology, clinical pharmacologyReview
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
10 authors at 5 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundA nanocrystal intravenous (IV) formulation of meloxicam is being studied with the aim of providing postoperative analgesia.
methodsThis randomized, multicenter, double-blind, placebo-controlled trial evaluated meloxicam IV 30 mg or placebo (≤ 3 doses) in 219 subjects undergoing abdominoplasty. The primary endpoint was the summed pain intensity difference over 24 hours postdose (SPID
resultsMeloxicam IV-treated subjects had a statistically significant reduction in the least squares mean of SPID
conclusionMeloxicam IV provided sustained pain relief and generally was well tolerated in subjects with moderate-to-severe pain following abdominoplasty.
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.