Evidence map›Paper›PMID 30276003›Full record

ArticleJournal of gastric cancer2018

Who Can Perform Adjuvant Chemotherapy Treatment for Gastric Cancer? A Multicenter Retrospective Overview of the Current Status in Korea.

Jae-Seok Min, Chang Min Lee, Sung Il Choi, Kyung Won Seo, Do Joong Park, Yong Hae Baik, Myoung-Won Son, Won Hyuk Choi, Sungsoo Kim, Kyung Ho Pak and 5 more

Open access · hybridAbstract read
In one paragraph

Article in Journal of gastric cancer, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.7field-weighted citation impact, top 26% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 4 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors at 13 institutions in 1 country.

Jae-Seok MinDepartment of Surgery, Dongnam Institute of Radiological and Medical Sciences, Cancer Center, Busan, Korea.ORCID https://orcid.org/0000-0002-5798-4595
Chang Min LeeDepartment of Surgery, Korea University Medical Center, Korea University College of Medicine, Seoul, Korea.
Sung Il ChoiDepartment of Surgery, Kyung Hee University Hospital at Gangdong, Seoul, Korea.
Kyung Won SeoDepartment of Surgery, Kosin University College of Medicine, Busan, Korea.
Do Joong ParkDepartment of Surgery, Seoul National University Bundang Hospital, Seongnam, Korea.
Yong Hae BaikDepartment of Surgery, Dongguk University Hospital, Goyang, Korea.
Myoung-Won SonDepartment of Surgery, Soonchunhyang University Cheonan Hospital, Cheonan, Korea.
Won Hyuk ChoiDepartment of Surgery, Hallym University Kangdong Sacred Heart Hospital, Seoul, Korea.
Sungsoo KimDepartment of Surgery, Chosun University College of Medicine, Gwangju, Korea.
Kyung Ho PakDepartment of Surgery, Hallym University Dongtan Sacred Heart Hospital, Hwaseong, Korea.
Min Gyu KimDepartment of Surgery, Hanyang University Guri Hospital, Guri, Korea.
Joong-Min ParkDepartment of Surgery, Chung-Ang University College of Medicine, Seoul, Korea.
Sang Ho JeongDepartment of Surgery, Gyeongsang National University Hospital, Changwon, Korea.
Moon-Soo LeeDepartment of Surgery, Eulji University Hospital, Daejeon, Korea.
Sungsoo ParkDepartment of Surgery, Korea University Medical Center, Korea University College of Medicine, Seoul, Korea.
Korea University Medical Center · KRSeoul National University Bundang Hospital · KRChangwon National University · KRChosun University · KRDaejeon Eulji Medical Center, Eulji University · KRDongguk University · KRDongnam Institute of Radiological & Medical Sciences · KRHallym University · KRHallym University Dongtan Sacred Heart Hospital · KRHanyang University Guri Hospital · KRKosin University · KRKyung Hee University Hospital at Gangdong · KRSoonchunhyang University · KR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeTo investigate the current status of adjuvant chemotherapy (AC) regimens in Korea and the difference in efficacy of AC administered by surgical and medical oncologists in patients with stage II or III gastric cancers. MATERIALS AND

methodsWe performed a retrospective observational study among 1,049 patients who underwent curative resection and received AC for stage II and III gastric cancers between February 2012 and December 2013 at 29 tertiary referral university hospitals in Korea. To minimize the influence of potential confounders on selection bias, propensity score matching (PSM) was used based on binary logistic regression analysis. The 3-year disease-free survival (DFS) rates were compared between patients who received AC administered by medical oncologists or surgical oncologists.

resultsBetween February 2012 and December 2013 in Korea, the most commonly prescribed AC by medical oncologists was tegafur/gimeracil/oteracil (S-1, 47.72%), followed by capecitabine with oxaliplatin (XELOX, 16.33%). After performing PSM, surgical oncologists (82.74%) completed AC as planned more often than medical oncologists (75.9%), with statistical significance (P=0.036). No difference in the 3-year DFS rates of stage II (P=0.567) or stage III (P=0.545) gastric cancer was found between the medical and surgical oncologist groups.

conclusionsS-1 monotherapy and XELOX are a main stay of AC, regardless of whether the prescribing physician is a medical or surgical oncologist. The better compliance with AC by surgical oncologists is a valid reason to advocate that surgical oncologists perform the treatment of AC for stage II or III gastric cancers.

Indexed as

Adjuvant chemotherapyGastric cancer

Identifiers

PMID30276003
PMCPMC6160523
OpenAlexW2891052436

What OpenQuestion holds

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LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.