ArticleThe journal of venomous animals and toxins including tropical diseases2018
Neolignans isolated from twigs of
Article in The journal of venomous animals and toxins including tropical diseases, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.
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Who cites it
5 citing papers in PubMed, 12 citations in OpenAlex.
- Synthesis of a dehydrodieugenol B derivative as a lead compound for visceral leishmaniasis-mechanism of action andAntimicrobial agents and chemotherapy · 2024Article
- Eugenol-Rich Essential Oil fromPharmaceuticals (Basel, Switzerland) · 2023Article
- Evaluating the Antischistosomal Activity of Dehydrodieugenol B and Its Methyl Ether Isolated fromACS omega · 2023Article
- Antileishmanial Effects of Acetylene Acetogenins from Seeds ofMolecules (Basel, Switzerland) · 2022Article
- Discovery of New Hits as Antitrypanosomal Agents by In Silico and In Vitro Assays Using Neolignan-Inspired Natural Products fromMolecules (Basel, Switzerland) · 2021Article
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Authors and funding
8 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundThe therapeutic arsenal for the treatment of Leishmaniasis is limited and includes toxic compounds (antimonials, amphotericin B, pentamidine and miltefosine). Given these aspects, the search for new compounds based on floristic biodiversity is crucial. In the present work, we report the isolation, characterization and antileishmanial activity of six related neolignans (
methodsDried and powdered twigs of
resultsDereplication procedures followed by chemical characterization of isolated compounds by NMR enabled the identification of related neolignans
conclusionThis study highlights compound
Indexed as
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