Evidence map›Paper›PMID 30275800›Full record

ArticleContrast media & molecular imaging2018

Parameters Influencing PET Imaging Features: A Phantom Study with Irregular and Heterogeneous Synthetic Lesions.

Francesca Gallivanone, Matteo Interlenghi, Daniela D'Ambrosio, Giuseppe Trifirò, Isabella Castiglioni

Abstract read
In one paragraph

Article in Contrast media & molecular imaging, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers.

0numbers the graph read from it
0cells of the map it votes in
24citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

24 citing papers in PubMed.

  1. Article
  2. Enhancing PET/CT target assessment with porous 3D printed grids: a pilot study.Physical and engineering sciences in medicine · 2026
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  11. A methodological framework for AI-assisted diagnosis of active aortitis using radiomic analysis of FDG PET-CT images: Initial analysis.Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2022
    Article
  12. Article
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  16. Review
  17. Article
  18. Repeatability ofJournal of nuclear medicine : official publication, Society of Nuclear Medicine · 2021
    Article
  19. Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Francesca GallivanoneInstitute of Molecular Bioimaging and Physiology, National Research Council (IBFM-CNR), Milan, Italy.ORCID 0000-0001-6559-6157
Matteo InterlenghiInstitute of Molecular Bioimaging and Physiology, National Research Council (IBFM-CNR), Milan, Italy.ORCID 0000-0002-3066-4276
Daniela D'AmbrosioMedical Physics Unit, IRCCS Fondazione S. Maugeri, Pavia, Italy.ORCID 0000-0003-1485-6259
Giuseppe TrifiròNuclear Medicine Unit, IRCCS Fondazione S. Maugeri, Pavia, Italy.
Isabella CastiglioniInstitute of Molecular Bioimaging and Physiology, National Research Council (IBFM-CNR), Milan, Italy.ORCID 0000-0001-7191-5417

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Aim: To evaluate reproducibility and stability of radiomic features as effects of the use of different volume segmentation methods and reconstruction settings. The potential of radiomics in really capturing the presence of heterogeneous tumor uptake and irregular shape was also investigated. Materials and Methods: An anthropomorphic phantom miming real clinical situations including synthetic lesions with irregular shape and nonuniform radiotracer uptake was used. Results: The choice of the segmentation method has a strong impact on the stability of radiomic features (less than 20% can be considered stable features). Reconstruction affects the estimate of radiomic features (only 26% are stable). Thirty-one radiomic features (53%) resulted to be reproducible, 11 of them are able to discriminate heterogeneity. Among these, we found a subset of 3 radiomic features strongly correlated with GS heterogeneity index that can be suggested as good features for retrospective evaluations.

Indexed as

Phantoms, ImagingPositron-Emission TomographyHumansImage Processing, Computer-AssistedReproducibility of Results

Identifiers

PMID30275800
PMCPMC6151367

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.