Evidence map›Paper›PMID 30275612›Full record

ArticleTetrahedron letters2018

dM-Dim for Carboxylic Acid Protection.

Shahien Shahsavari, Travis Wigstrom, James Gooding, Chase McNamara, Shiyue Fang

Abstract read
In one paragraph

Article in Tetrahedron letters, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.7field-weighted citation impact, top 36% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 6 citations in OpenAlex.

  1. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Shahien ShahsavariDepartment of Chemistry, Michigan Technological University, 1400 Townsend Drive, Houghton, MI 49931 USA.
Travis WigstromDepartment of Chemistry, Michigan Technological University, 1400 Townsend Drive, Houghton, MI 49931 USA.
James GoodingDepartment of Chemistry, Michigan Technological University, 1400 Townsend Drive, Houghton, MI 49931 USA.
Chase McNamaraDepartment of Chemistry, Michigan Technological University, 1400 Townsend Drive, Houghton, MI 49931 USA.
Shiyue FangDepartment of Chemistry, Michigan Technological University, 1400 Townsend Drive, Houghton, MI 49931 USA.
Michigan Technological University · US

Funding

Synthesis of Sensitive Epitranscriptomically Modified RNAsR15GM109288 · NIGMS · MICHIGAN TECHNOLOGICAL UNIVERSITY · PI FANG, SHIYUE · 2014 to 2024
$1.3M
NIGMS NIH HHS R15 GM109288
6 · The paper itself

Abstract

The 1,3-dithian-2-yl-methyl (Dim) and its analogous groups including dimethyl-Dim (dM-Dim) can provide a new dimension of orthogonality for carboxylic acid protection. They can be deprotected under nearly neutral oxidative conditions. In this paper, the protection of carboxylic acid with dM-Dim, deprotection of dM-Dim ester with sodium periodate, stability of dM-Dim protected carboxylic acid under acidic and basic conditions, and selective deprotection of dM-Dim protected carboxylic acids in the presence of tertiary butyl and methyl esters are presented.

Indexed as

carboxylic aciddM-Dimoxidationprotecting group

Identifiers

PMID30275612
PMCPMC6161831
OpenAlexW2795327212

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.