Evidence map›Paper›PMID 30275598›Full record

ArticleInorganica chimica acta2017

Near-Infrared Fluorescent Probe for Sensitive Detection of Pb(II) Ions in Living Cells.

Jianheng Bi, Mingxi Fang, Jianbo Wang, Shuai Xia, Yibin Zhang, Jingtuo Zhang, Giri Vegesna, Shuwei Zhang, Marina Tanasova, Fen-Tair Luo and 1 more

Abstract read
In one paragraph

Article in Inorganica chimica acta, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Jianheng BiDepartment of Chemistry, Michigan Technological University, Houghton, MI 49931.
Mingxi FangDepartment of Chemistry, Michigan Technological University, Houghton, MI 49931.
Jianbo WangCollege of Biological, Chemical Sciences and Engineering, Jiaxing University, Jiaxing 314001, China.
Shuai XiaDepartment of Chemistry, Michigan Technological University, Houghton, MI 49931.
Yibin ZhangDepartment of Chemistry, Michigan Technological University, Houghton, MI 49931.
Jingtuo ZhangDepartment of Chemistry, Michigan Technological University, Houghton, MI 49931.
Giri VegesnaDepartment of Chemistry, Michigan Technological University, Houghton, MI 49931.
Shuwei ZhangDepartment of Chemistry, Michigan Technological University, Houghton, MI 49931.
Marina TanasovaDepartment of Chemistry, Michigan Technological University, Houghton, MI 49931.
Fen-Tair LuoInstitute of Chemistry, Academia Sinica, Taipei, Taiwan 11529, Republic of China.
Haiying LiuDepartment of Chemistry, Michigan Technological University, Houghton, MI 49931.

Funding

Ratiometric Near-infrared Fluorescent Probes for Lysosomal pH in Living CellsR15GM114751 · NIGMS · MICHIGAN TECHNOLOGICAL UNIVERSITY · PI LIU, HAIYING · 2015 to 2019
$798k
NIGMS NIH HHS R15 GM114751
6 · The paper itself

Abstract

A new near-infrared fluorescent probe (NIR-PbP) for sensitive detection of Pb(II) ions in solution and living cells has been rationally designed and synthesized. The NIR-PbP is inherently non-fluorescent and gains fluorescence in the presence Pb(II) ions. The ion detection is based on Pb(II)-induced unmasking the fluorophore through the opening of the spyrocycle, with more than 500-fold fluorescence for sub-micromolar Pb(II) concentration. The NIR-PbP has high sensitivity, good photo-stability, low detection limit, and reversible response to Pb(II) ions.

Indexed as

FluorescenceFluorescent probeNear-infrared emissionPb(II) ions

Identifiers

PMID30275598
PMCPMC6162053

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.