Evidence map›Paper›PMID 30275511›Full record

ArticleNature microbiology2018

Structural basis for usher activation and intramolecular subunit transfer in P pilus biogenesis in Escherichia coli.

Natalie S Omattage, Zengqin Deng, Jerome S Pinkner, Karen W Dodson, Fredrik Almqvist, Peng Yuan, Scott J Hultgren

Abstract read
In one paragraph

Article in Nature microbiology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
1.9field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 25 citations in OpenAlex.

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  7. Structure-function correlates of fibrinogen binding byProceedings of the National Academy of Sciences of the United States of America · 2023
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 2 countries.

Natalie S OmattageDepartment of Molecular Microbiology, Washington University in St Louis, St Louis, MO, USA.
Zengqin DengDepartment of Cell Biology and Physiology, Washington University in St Louis, St Louis, MO, USA.ORCID http://orcid.org/0000-0002-5658-2068
Jerome S PinknerDepartment of Molecular Microbiology, Washington University in St Louis, St Louis, MO, USA.
Karen W DodsonDepartment of Molecular Microbiology, Washington University in St Louis, St Louis, MO, USA.
Fredrik AlmqvistDepartment of Chemistry, Umeå University, Umeå, Sweden.
Peng YuanDepartment of Cell Biology and Physiology, Washington University in St Louis, St Louis, MO, USA. yuanp@wustl.edu.ORCID http://orcid.org/0000-0002-5660-225X
Scott J HultgrenDepartment of Molecular Microbiology, Washington University in St Louis, St Louis, MO, USA. Hultgren@wustl.edu.ORCID http://orcid.org/0000-0001-8785-564X
Washington University in St. Louis · USUmeå University · SE

Funding

Overall EvaluationP41GM103403 · NIGMS · CORNELL UNIVERSITY · PI EALICK, STEVEN E · 2012 to 2017
$14.3M
PATHOGENIC FIBER FORMATION IN BACTERIA: STRUCTURAL BASISR01AI048689 · NIAID · WASHINGTON UNIVERSITY · PI HULTGREN, SCOTT J. · 2001 to 2020
$7.6M
CHAPERONE-ASSISTED PILI ASSEMBLY IN PATHOGENIC E. COLIR01AI029549 · NIAID · WASHINGTON UNIVERSITY · PI HULTGREN, SCOTT J., YUAN, PENG · 1991 to 2023
$5.7M
Pathogenic Fiber Formation in Bacteria: Structural BasisR37AI048689 · NIAID · WASHINGTON UNIVERSITY · PI SCOTT J. HULTGREN · 2021 to 2026
$2.9M
Pixel Array Detector for Macromolecular CrystallographyS10OD021527 · OD · CORNELL UNIVERSITY · PI EALICK, STEVEN E · 2016 to 2016
$2.0M
Pixel Array Detector for X-ray CrystallographyS10RR029205 · NCRR · CORNELL UNIVERSITY · PI EALICK, STEVEN E · 2010 to 2010
$1.8M
NCRR NIH HHS S10 RR029205NIAID NIH HHS R01 AI029549NIAID NIH HHS R01 AI048689NIAID NIH HHS R37 AI048689NIGMS NIH HHS P41 GM103403NIH HHS S10 OD021527
6 · The paper itself

Abstract

Chaperone-usher pathway pili are extracellular proteinaceous fibres ubiquitously found on Gram-negative bacteria, and mediate host-pathogen interactions and biofilm formation critical in pathogenesis in numerous human diseases

Indexed as

Escherichia coliEscherichia coli ProteinsFimbriae, BacterialModels, MolecularMolecular ChaperonesPeriplasmic ProteinsPorinsProtein BindingProtein ConformationProtein DomainsatpG protein, E coliEscherichia coli ProteinsMolecular ChaperonesPapD protein, E coliPeriplasmic ProteinsPorins

Identifiers

PMID30275511
PMCPMC6258349
OpenAlexW2970932648

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.