Evidence map›Paper›PMID 30275508›Full record

ArticleScientific reports2018

Genetic structure and polymorphisms of Gelao ethnicity residing in southwest china revealed by X-chromosomal genetic markers.

Pengyu Chen, Guanglin He, Xing Zou, Mengge Wang, Haibo Luo, Limei Yu, Xijie Hu, Mijia Xia, Hongyan Gao, Jian Yu and 2 more

Open access · goldAbstract read
In one paragraph

Article in Scientific reports, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
2.9field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 23 citations in OpenAlex.

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4 · The record

Corrections and comments

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5 · Who and what money

Authors and funding

12 authors at 3 institutions in 1 country.

Pengyu ChenCenter of Forensic Expertise, Affiliated Hospital of Zunyi Medical University, Zunyi, Guizhou, China.
Guanglin HeInstitute of Forensic Medicine, West China School of Basic Medical Sciences & Forensic Medicine, Sichuan University, Chengdu, Sichuan, China.
Xing ZouInstitute of Forensic Medicine, West China School of Basic Medical Sciences & Forensic Medicine, Sichuan University, Chengdu, Sichuan, China.
Mengge WangInstitute of Forensic Medicine, West China School of Basic Medical Sciences & Forensic Medicine, Sichuan University, Chengdu, Sichuan, China.
Haibo LuoInstitute of Forensic Medicine, West China School of Basic Medical Sciences & Forensic Medicine, Sichuan University, Chengdu, Sichuan, China.
Limei YuKey Laboratory of Cell Engineering in Guizhou Province, Zunyi, Guizhou, China.
Xijie HuKey Laboratory of Cell Engineering in Guizhou Province, Zunyi, Guizhou, China.
Mijia XiaJudicial Authentication Institution, First People's Hospital of Zunyi City, Zunyi, Guizhou, China.
Hongyan GaoCenter of Forensic Expertise, Affiliated Hospital of Zunyi Medical University, Zunyi, Guizhou, China.
Jian YuCenter of Forensic Expertise, Affiliated Hospital of Zunyi Medical University, Zunyi, Guizhou, China.
Yiping HouInstitute of Forensic Medicine, West China School of Basic Medical Sciences & Forensic Medicine, Sichuan University, Chengdu, Sichuan, China. profhou@yahoo.cn.
Yanyan HanDepartment of Nutrition and Food Hygiene, School of Public Health, Zunyi Medical University, Zunyi, Guizhou, China. hanyanyan1984@126.com.
West China Medical Center of Sichuan University · CNZunyi Medical University · CNFirst People’s Hospital of Zunyi · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

X-chromosome short tandem repeat markers (X-STRs), due to their special inheritance models, physical location on a single chromosome and the absence of recombination in male meiosis, play an important role in forensic and population genetics. While a series of genetic analyses focusing on the genetic diversity and forensic characteristics of X-STRs are well studied for ethnically/linguistically diverse and demographically large Chinese populations, genetic evidence from Gelao ethnicity is still sparse. Here, we genotyped the first batch of 19 X-STRs in 513 Chinese Gelao individuals (265 females and 248 males), and reported genetic polymorphisms, forensic characteristics based on the single locus and seven linkage groups. DXS10135 with the highest PIC (0.9106) and LG1 (DXS10148-DXS10135-DXS8378) with the largest HD (0.9970) are polymorphic and informative. The CPDs in Gelao males and females are respectively larger than 0.999999999997095 and 0.99999999999999999999918, and the combined MECs are larger than 0.999999975715109. Subsequently, we investigated the population relationships among 14 Chinese populations based on 19 X-STRs and among 23 populations based on 11 overlapped X-STRs. Our results revealed genetic differentiations among Tibeto-Burman, Altaic and other Chinese homogenous populations, and demonstrated that Guizhou Gelao has the genetically closer relationships with Han Chinese and geographically close Guizhou Miao.

Indexed as

Chromosomes, Human, XEthnicityGenetic MarkersGenetic VariationGenotypeChinaFemaleGenetics, PopulationGenetic StructuresHumansMaleTandem Repeat SequencesGenetic Markers

Identifiers

PMID30275508
PMCPMC6167355
OpenAlexW2893371377

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