ArticleScientific reports2018
Relationship between mean platelet volume and metabolic syndrome in Chinese patients.
Article in Scientific reports, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers, 1 of them a synthesis that pooled it.
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Who cites it
17 citing papers in PubMed, 1 synthesis or guideline pooled it, 26 citations in OpenAlex.
- Mean platelet volume levels in children with sleep-disordered breathing: a meta-analysis.BMC pediatrics · 2020Pooled it
- Article
- [Association Between Blood Routine Index and Metabolic Syndrome in High-altitude Tibetan Population].Sichuan da xue xue bao. Yi xue ban = Journal of Sichuan University. Medical science edition · 2026Article
- Reduced platelet count in mice protects against glucose intolerance and beta cell loss during a long-term high-fat diet.Frontiers in immunology · 2026Article
- Mean platelet volume as a biomarker of anemia and platelet disorders among metabolic syndrome patients in Northwest Ethiopia.Scientific reports · 2025Article
- Application of autologous platelet rich plasma in Sun's procedure for acute type A aortic dissection under moderate hypothermia.Frontiers in cardiovascular medicine · 2025Article
- Review
- Investigating the relationship between haematological parameters and metabolic syndrome: A population-based study.Endocrinology, diabetes & metabolism · 2023Article
- Insulin Resistance-Induced Platelet Hyperactivity and a Potential Biomarker Role of Platelet Parameters: A Narrative Review.Diabetes, metabolic syndrome and obesity : targets and therapy · 2023Review
- Exercise Training andPlants (Basel, Switzerland) · 2022Article
- Effects of Nutrients on Platelet Function: A Modifiable Link between Metabolic Syndrome and Neurodegeneration?Biomolecules · 2021Review
- Albuminuria Is Associated with Hepatic Iron Load in Patients with Non-Alcoholic Fatty Liver Disease and Metabolic Syndrome.Journal of clinical medicine · 2021Article
- Platelet Measurements and Type 2 Diabetes: Investigations in Two Population-Based Cohorts.Frontiers in cardiovascular medicine · 2020Article
- Gender impact on the correlations between Graves' hyperthyroidism and hyperuricemia in Chinese.Irish journal of medical science · 2019Article
- Gender- and Age-Specific Differences in the Association of Hyperuricemia and Hypertension: A Cross-Sectional Study.International journal of endocrinology · 2019Article
- Gender-Specific Differences on the Association of Hypertension with Subclinical Thyroid Dysfunction.International journal of endocrinology · 2019Article
- Serum bilirubin is negatively associated with white blood cell count.Clinics (Sao Paulo, Brazil) · 2019Article
Corrections and comments
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Authors and funding
19 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Mean platelet volume (MPV) is a determinant of activation and variability of platelets (PLT). The focus of this study was to to investigate MPV values in patients with and without metabolic syndrome (MS). It also evaluates the association between them. There are close connections among MPV, MS, and cardiometabolic risk. We compiled age, body mass index, blood cell counts, MPV, and other data of 59976 self-reported healthy volunteers (28428 male, 31548 female), 24.65% of who have MS. The mean age of the group was 48.21 years old. The data was grouped by sex and values of data between men and women groups were analyzed by independent sample's t-test. The relationship between sex and MS was evaluated by chi-square tests. Crude odd ratios of MS between MPV quartiles and 95% confidence intervals were analyzed by binary logistic regression in this study. We found women had higher levels of MPV (10.09 vs. 9.98, P < 0.01) and PLT (228.68 vs. 212.11, P < 0.01) than men. In females, the prevalence of MS was higher in low MPV group than in high MPV groups. The odds of having MS were significantly lower in higher MPV quartiles compared with MPV Quartile 1 in women (Adjusted OR < 1, P < 0.01). This study indicated that MS was inversely associated with MPV in females only.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.