Evidence map›Paper›PMID 30275404›Full record

ReviewMarine drugs2018

Biological and Chemical Diversity of Ascidian-Associated Microorganisms.

Lei Chen, Jin-Shuang Hu, Jia-Lei Xu, Chang-Lun Shao, Guang-Yu Wang

Abstract readReview
In one paragraph

Review in Marine drugs, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.

0numbers the graph read from it
0cells of the map it votes in
22citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

22 citing papers in PubMed.

  1. Article
  2. In-Depth Exploration of Chemical Constituents fromMolecules (Basel, Switzerland) · 2025
    Article
  3. Article
  4. Review
  5. Review
  6. Article
  7. Article
  8. Article
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  12. Review
  13. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Lei ChenDepartment of Bioengineering, School of Marine Science and Technology, Harbin Institute of Technology, Weihai 264209, China. chenlei@hitwh.edu.cn.
Jin-Shuang HuDepartment of Bioengineering, School of Marine Science and Technology, Harbin Institute of Technology, Weihai 264209, China. m17862700663@163.com.
Jia-Lei XuDepartment of Bioengineering, School of Marine Science and Technology, Harbin Institute of Technology, Weihai 264209, China. Xvjialei2016@126.com.
Chang-Lun ShaoLaboratory of Marine Drugs, The Ministry of Education of China, School of Medicine and Pharmacy, Ocean University of China, Qingdao 266003, China. shaochanglun@163.com.
Guang-Yu WangDepartment of Bioengineering, School of Marine Science and Technology, Harbin Institute of Technology, Weihai 264209, China. wangguangyu@hitwh.edu.cn.ORCID 0000-0002-9973-4738

Funding

Discipline Construction Guide Foundation in Harbin Institute of Technology at Weihai WH20150204 and WH20160205National Natural Science Foundation of China 31300009Natural Scientific Research Innovation Foundation in Harbin Institute of Technology HIT. NSRIF. 2014127
6 · The paper itself

Abstract

Ascidians are a class of sessile filter-feeding invertebrates, that provide unique and fertile niches harboring various microorganisms, such as bacteria, actinobacteria, cyanobacteria and fungi. Over 1000 natural products, including alkaloids, cyclic peptides, and polyketides, have been isolated from them, which display diverse properties, such as antibacterial, antifungal, antitumor, and anti-inflammatory activities. Strikingly, direct evidence has confirmed that ~8% of natural products from ascidians are actually produced by symbiotic microorganisms. In this review, we present 150 natural products from microorganisms associated with ascidians that have been reported up to 2017.

Indexed as

AnimalsAnti-Infective AgentsBiological ProductsHumansUrochordataAnti-Infective AgentsBiological Productsalkaloidsascidianbioactivitydiversitymicroorganismpolyketides

Identifiers

PMID30275404
PMCPMC6212887

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.