ReviewJournal of clinical medicine2018
Acute Kidney Injury in Pregnancy: The Need for Higher Awareness. A Pragmatic Review Focused on What Could Be Improved in the Prevention and Care of Pregnancy-Related AKI, in the Year Dedicated to Women and Kidney Diseases.
Review in Journal of clinical medicine, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers, 1 of them a synthesis that pooled it.
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Who cites it
25 citing papers in PubMed, 1 synthesis or guideline pooled it, 46 citations in OpenAlex.
- Pregnancy-related acute kidney injury in the African continent: where do we stand? A systematic review.Journal of nephrology · 2022Pooled it
- Article
- Pregnancy-associated acute kidney injury - consensus report of the 32nd Acute Disease Quality Initiative workgroup.Nature reviews. Nephrology · 2025Article
- Temporal trends and clinical characteristics associated with pregnancy-related acute kidney injury in England: a population-based cohort study.AJOG global reports · 2025Article
- Outcomes of pregnancy-related acute kidney injury: A retrospective study in the obstetric critical care unit at Kenyatta National Hospital 2020 to 2023.PLOS global public health · 2025Article
- Characteristics and outcome of pregnancy-related acute kidney injury in a teaching hospital in a low-resource setting: a five-year retrospective review.BMC nephrology · 2024Article
- Development of a formula for estimated glomerular filtration rate in pregnant women from physiological hyperfiltration of serum creatinine.Scientific reports · 2024Article
- Acute Kidney Injury: Magnitude and Predictors of Maternal Outcomes among Pre-Eclamptic and Eclamptic Women in Mwanza, Tanzania.The East African health research journal · 2024Article
- Pregnancy-related acute kidney injury leads to hypertension, reduced kidney function and cognitive impairment in postpartum rats.Frontiers in physiology · 2024Article
- Miscarriage-Related Acute Kidney Injury: A Case Report.International medical case reports journal · 2024Article
- Characteristics and Outcomes of Patients With Pregnancy-Related End-Stage Kidney Disease.JAMA network open · 2023Article
- Ethnic disparities in pregnancy-related acute kidney injury in a United Kingdom population.Journal of nephrology · 2023Article
- Kidney Biopsy in Pregnant Women with Glomerular Diseases: Focus on Lupus Nephritis.Journal of clinical medicine · 2023Review
- Kidney-placenta crosstalk in health and disease.Clinical kidney journal · 2022Review
- The Hypertensive Disorders of Pregnancy: A Focus on Definitions for Clinical Nephrologists.Journal of clinical medicine · 2022Review
- Renal Outcomes of Pregnancy-Related Acute Kidney Injury: a Single Centre Experience in India.Maedica · 2022Article
- Acute kidney injury during pregnancy leads to increased sFlt-1 and sEng and decreased renal T regulatory cells in pregnant rats with HELLP syndrome.Biology of sex differences · 2020Article
- Article
- Acute kidney injury associated with preeclampsia or hemolysis, elevated liver enzymes, and low platelets syndrome.Pregnancy hypertension · 2020Article
- Acute Kidney Injury in Pregnancies Complicated With Preeclampsia or HELLP Syndrome.Frontiers in medicine · 2020Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
13 authors at 10 institutions in 9 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Pregnancy-related acute kidney injury (pAKI), preeclampsia (PE), and the hypertensive disorders of pregnancy are closely related conditions, which are, in turn, frequently linked to pre-existing and often non-diagnosed chronic kidney disease (CKD). The current literature and research mainly underline the effects of pregnancy complications on the offspring; this review strongly emphasizes the maternal health as well. These conditions not only negatively affect pregnancy outcomes, but have a relevant effect on the future health of affected mothers and their children. Therefore, dedicated diagnostic and follow-up programs are needed, for optimizing materno-foetal health and reducing the impact of pregnancy-related problems in the mothers and in the new generations. This narrative review, performed on the occasion of the 2018 World Kidney Day dedicated to women's health, focuses on three aspects of the problem. Firstly, the risk of AKI in the hypertensive disorders of pregnancy (the risk is the highest in developing countries; however PE is the main cause of pregnancy related AKI worldwide). Secondly, the effect of AKI and the hypertensive disorders of pregnancy on the development of CKD in the mother and offspring: long-term risks are increased; the entity and the trajectories are still unknown. Thirdly, the role of CKD in the pathogenesis of AKI and the hypertensive disorders of pregnancy: CKD is a major risk factor and the most important element in the differential diagnosis; pregnancy is a precious occasion for early diagnosis of CKD. Higher awareness on the importance of AKI in pregnancy is needed to improve short and long term outcomes in mothers and children.
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