Evidence map›Paper›PMID 30275391›Full record

ArticleMarine drugs2018

Aurantoside C Targets and Induces Apoptosis in Triple Negative Breast Cancer Cells.

Sumi Shrestha, Anabel Sorolla, Jane Fromont, Pilar Blancafort, Gavin R Flematti

Open access · goldAbstract read
In one paragraph

Article in Marine drugs, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed, 1 pooled it
2.2field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 1 synthesis or guideline pooled it, 23 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Review
  4. Review
  5. Article
  6. Review
  7. Therapeutic Benefits of Selenium in Hematological Malignancies.International journal of molecular sciences · 2022
    Review
  8. Review
  9. Article
  10. Article
  11. MAPK signaling pathway-targeted marine compounds in cancer therapy.Journal of cancer research and clinical oncology · 2021
    Review
  12. Review
  13. Article
  14. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Sumi ShresthaSchool of Molecular Sciences, The University of Western Australia, Crawley, WA 6009, Australia. sumi.shrestha@research.uwa.edu.au.
Anabel SorollaCancer Epigenetics, Harry Perkins Institute of Medical Research, QEII Medical Centre and Centre for Medical Research, The University of Western Australia, Crawley, WA 6009, Australia. anabel.sorollabardaji@perkins.uwa.edu.au.
Jane FromontWestern Australian Museum, Welshpool, WA 6106, Australia. jane.fromont@museum.wa.gov.au.
Pilar BlancafortCancer Epigenetics, Harry Perkins Institute of Medical Research, QEII Medical Centre and Centre for Medical Research, The University of Western Australia, Crawley, WA 6009, Australia. pilar.blancafort@uwa.edu.au.
Gavin R FlemattiSchool of Molecular Sciences, The University of Western Australia, Crawley, WA 6009, Australia. gavin.flematti@uwa.edu.au.
The University of Western Australia · AUAustralian Museum · AU

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Triple negative breast cancer (TNBC) is a subtype of breast cancers that currently lacks effective targeted therapy. In this study, we found that aurantoside C (C828), isolated from the marine sponge

Indexed as

AnimalsAntineoplastic AgentsApoptosisCell Line, TumorFemaleGlycosidesHumansMCF-7 CellsPhosphorylationPoriferaPyrrolidinonesSignal TransductionS PhaseTriple Negative Breast NeoplasmsAntineoplastic Agentsaurantoside CGlycosidesPyrrolidinonesapoptosisaurantoside Ccell cycle analysismarine spongetriple negative breast cancer

Identifiers

PMID30275391
PMCPMC6213655
OpenAlexW2895617348

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.