Evidence map›Paper›PMID 30275388›Full record

ArticleMarine drugs2018

AbeTx1 Is a Novel Sea Anemone Toxin with a Dual Mechanism of Action on Shaker-Type K⁺ Channels Activation.

Diego J B Orts, Steve Peigneur, Laíz Costa Silva-Gonçalves, Manoel Arcisio-Miranda, José Eduardo P W Bicudo, Jan Tytgat

Open access · goldAbstract read
In one paragraph

Article in Marine drugs, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
0.8field-weighted citation impact, top 27% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 20 citations in OpenAlex.

  1. Review
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  5. Voltage-Gated KMarine drugs · 2024
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 2 countries.

Diego J B OrtsDepartment of Physiology, Institute of Biosciences, University of São Paulo, 05508-090 São Paulo, Brazil. diego.orts@usp.br.
Steve PeigneurToxicology and Pharmacology, University of Leuven (KU Leuven), Campus Gasthuisberg O&N2, Herestraat 49, P.O. Box 922, 3000 Leuven, Belgium. steve.peigneur@pharm.kuleuven.be.ORCID 0000-0003-0504-5702
Laíz Costa Silva-GonçalvesLaboratório de Neurobiologia Estrutural e Funcional (LaNEF), Departamento de Biofísica, Universidade Federal de São Paulo, 04023-062 São Paulo, Brazil. laiz.lcs@gmail.com.
Manoel Arcisio-MirandaLaboratório de Neurobiologia Estrutural e Funcional (LaNEF), Departamento de Biofísica, Universidade Federal de São Paulo, 04023-062 São Paulo, Brazil. arcisio.miranda@unifesp.br.ORCID 0000-0002-1086-086X
José Eduardo P W BicudoDepartment of Physiology, Institute of Biosciences, University of São Paulo, 05508-090 São Paulo, Brazil. jebicudo@usp.br.
Jan TytgatToxicology and Pharmacology, University of Leuven (KU Leuven), Campus Gasthuisberg O&N2, Herestraat 49, P.O. Box 922, 3000 Leuven, Belgium. jan.tytgat@pharm.kuleuven.be.
KU Leuven · BEUniversidade de São Paulo · BRUniversidade Federal de São Paulo · BR

Funding

Conselho Nacional de Desenvolvimento Científico e Tecnológico 142066/2014-1Fundação de Amparo à Pesquisa do Estado de São Paulo 2009/07128-7 and 2011/21031-6Fundação de Amparo à Pesquisa do Estado de São Paulo 2016/17951-6 and 2016/13368-4
6 · The paper itself

Abstract

Voltage-gated potassium (K

Indexed as

Amino AcidsAmino Acid SequenceAnimalsCnidarian VenomsPeptidesPotassiumPotassium Channel BlockersPotassium Channels, Voltage-GatedSea AnemonesSequence AlignmentToxins, BiologicalAmino AcidsCnidarian VenomsPeptidesPotassiumPotassium Channel BlockersPotassium Channels, Voltage-GatedToxins, BiologicalActinia bermudensisAlanine point mutationpotassium channelsea anemone neurotoxintype 6 KV-toxins

Identifiers

PMID30275388
PMCPMC6213216
OpenAlexW2895006667

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.