Evidence map›Paper›PMID 30275385›Full record

ArticleInternational journal of molecular sciences2018

Ghrelin in Serum and Urine of Post-Partum Women with Gestational Diabetes Mellitus.

Żaneta Kimber-Trojnar, Jolanta Patro-Małysza, Katarzyna E Skórzyńska-Dziduszko, Jan Oleszczuk, Marcin Trojnar, Radzisław Mierzyński, Bożena Leszczyńska-Gorzelak

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
0.9field-weighted citation impact, top 28% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 18 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Review
  5. Article
  6. Incretins as a Potential Treatment Option for Gestational Diabetes Mellitus.International journal of molecular sciences · 2022
    Review
  7. Novel Biomolecules in the Pathogenesis of Gestational Diabetes Mellitus 2.0.International journal of molecular sciences · 2022
    Review
  8. Novel Biomolecules in the Pathogenesis of Gestational Diabetes Mellitus.International journal of molecular sciences · 2021
    Review
  9. Review
  10. Article
  11. Article
  12. Article
  13. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Żaneta Kimber-TrojnarDepartment of Obstetrics and Perinatology, Medical University of Lublin, Lublin 20-090, Poland. zkimber@poczta.onet.pl.ORCID 0000-0001-7295-0409
Jolanta Patro-MałyszaDepartment of Obstetrics and Perinatology, Medical University of Lublin, Lublin 20-090, Poland. jolapatro@wp.pl.ORCID 0000-0002-4118-7698
Katarzyna E Skórzyńska-DziduszkoDepartment of Human Physiology, Medical University of Lublin, Lublin 20-080, Poland. katarzyna.skorzynska-dziduszko@umlub.pl.ORCID 0000-0002-8718-1187
Jan OleszczukDepartment of Obstetrics and Perinatology, Medical University of Lublin, Lublin 20-090, Poland. jan.oleszczuk@umlub.pl.
Marcin TrojnarDepartment of Internal Medicine, Medical University of Lublin, Lublin 20-081, Poland. marcin.trojnar@umlub.pl.
Radzisław MierzyńskiDepartment of Obstetrics and Perinatology, Medical University of Lublin, Lublin 20-090, Poland. radekm1969@gmail.com.
Bożena Leszczyńska-GorzelakDepartment of Obstetrics and Perinatology, Medical University of Lublin, Lublin 20-090, Poland. b.leszczynska@umlub.pl.
Medical University of Lublin · PL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Women with a previous history of gestational diabetes mellitus (GDM) have a significantly increased risk of developing type 2 diabetes, obesity, and cardiovascular diseases in the future. The aim of the study was to evaluate ghrelin concentrations in serum and urine in the GDM group in the early post-partum period, with reference to laboratory results, body composition, and hydration status. The study subjects were divided into two groups, that is, 28 healthy controls and 26 patients with diagnosed GDM. The maternal body composition and hydration status were evaluated by the bioelectrical impedance analysis (BIA) method. The concentrations of ghrelin in the maternal serum and urine were determined via enzyme-linked immunosorbent assay (ELISA). The laboratory and BIA results of the mothers with GDM were different from those without GDM. Urine ghrelin positively correlated with serum ghrelin and high-density lipoprotein cholesterol (HDL) levels in healthy mothers. There were direct correlations between urine ghrelin and HDL as well as triglycerides levels in the GDM group. Neither the lean tissue index nor body cell mass index were related to the serum ghrelin concentrations in this group. Only the urine ghrelin of healthy mothers correlated with the fat tissue index. Our results draw attention to urine as an easily available and appropriable biological material for further studies.

Indexed as

AdultDiabetes, GestationalFemaleGhrelinHumansPostpartum PeriodPregnancyGhrelinbioelectrical impedance analysisbody compositiongestational diabetes mellitusghrelinhydration status

Identifiers

PMID30275385
PMCPMC6213416
OpenAlexW2893466587

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.