Evidence map›Paper›PMID 30275368›Full record

ArticleNutrients2018

Reduced Carotenoid and Retinoid Concentrations and Altered Lycopene Isomer Ratio in Plasma of Atopic Dermatitis Patients.

Renata Lucas, Johanna Mihály, Gordon M Lowe, Daniel L Graham, Monika Szklenar, Andrea Szegedi, Daniel Töröcsik, Ralph Rühl

Open access · goldAbstract read
In one paragraph

Article in Nutrients, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
1.1field-weighted citation impact, top 28% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 24 citations in OpenAlex.

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  5. Characteristics of gut microbiota and serum metabolism in patients with atopic dermatitis.Skin research and technology : official journal of International Society for Bioengineering and the Skin (ISBS) [and] International Society for Digital Imaging of Skin (ISDIS) [and] International Society for Skin Imaging (ISSI) · 2024
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 2 countries.

Renata LucasDepartment of Dermatology, Faculty of Medicine, University of Debrecen, 4032 Debrecen, Hungary. renata.lucas@rocketmail.com.
Johanna MihályDepartment of Biochemistry and Molecular Biology, University of Debrecen, 4032 Debrecen, Hungary. johanna@med.unideb.hu.
Gordon M LoweSchool of Pharmacy and Biomolecular Sciences, Liverpool John Moores University, Byrom Street, Liverpool L3 3AF, UK. g.m.lowe@ljmu.ac.uk.
Daniel L GrahamSchool of Pharmacy and Biomolecular Sciences, Liverpool John Moores University, Byrom Street, Liverpool L3 3AF, UK. D.L.Graham@ljmu.ac.uk.
Monika SzklenarPaprika Bioanalytics BT, 4002 Debrecen, Hungary. monikaszklenar1@gmail.com.
Andrea SzegediDepartment of Dermatology, Faculty of Medicine, University of Debrecen, 4032 Debrecen, Hungary. aszegedi@med.unideb.hu.
Daniel TöröcsikDepartment of Dermatology, Faculty of Medicine, University of Debrecen, 4032 Debrecen, Hungary. dtorocsik@gmail.com.
Ralph RühlDepartment of Biochemistry and Molecular Biology, University of Debrecen, 4032 Debrecen, Hungary. ralphruehl@web.de.
University of Debrecen · HULiverpool John Moores University · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Carotenoids and retinoids are known to alter the allergic response with important physiological roles in the skin and the immune system. In the human organism various carotenoids are present, some of which are retinoid precursors. The bioactive derivatives of these retinoids are the retinoic acids, which can potently activate nuclear hormone receptors such as the retinoic acid receptor and the retinoid X receptor. In this study, we aimed to assess how plasma carotenoid and retinoid concentrations along with the ratio of their isomers are altered in atopic dermatitis (AD) patients (

Indexed as

AdolescentAdultbeta CaroteneCarotenoidsCase-Control StudiesDermatitis, AtopicFemaleHumansLuteinLycopeneMaleRetinoidsSignal TransductionTretinoinVitamin AYoung Adultbeta CaroteneCarotenoidsLuteinLycopeneRetinoidsTretinoinVitamin AZeaxanthinscarotenelycopeneRARretinoic acidretinoidRXRvitamin A

Identifiers

PMID30275368
PMCPMC6213761
OpenAlexW2883243145

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.