Evidence map›Paper›PMID 30275283›Full record

ArticleDiabetes care2018

Atherosclerosis and Microvascular Complications: Results From the Canadian Study of Longevity in Type 1 Diabetes.

Julie A Lovshin, Petter Bjornstad, Leif E Lovblom, Johnny-Wei Bai, Yuliya Lytvyn, Geneviève Boulet, Mohammed A Farooqi, Sam Santiago, Andrej Orszag, Daniel Scarr and 7 more

Open access · hybridAbstract read
In one paragraph

Article in Diabetes care, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 36 papers.

0numbers the graph read from it
0cells of the map it votes in
36citing papers in PubMed
6.0field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

36 citing papers in PubMed, 58 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Article
  5. Article
  6. Review
  7. Review
  8. Review
  9. Review
  10. Review
  11. Article
  12. Review
  13. Article
  14. Review
  15. Article
  16. Article
  17. Biomarkers of aging.Science China. Life sciences · 2023
    Review
  18. Article
  19. Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

17 authors at 6 institutions in 2 countries.

Julie A LovshinDivision of Endocrinology and Metabolism, Department of Medicine, University of Toronto, Toronto, Ontario, Canada julie.lovshin@sunnybrook.ca.ORCID 0000-0002-9171-8952
Petter BjornstadDivision of Endocrinology, Department of Pediatrics, University of Colorado, Aurora, CO.ORCID 0000-0002-5160-2947
Leif E LovblomLunenfeld-Tanenbaum Research Institute, Mount Sinai Hospital, Toronto, Ontario, Canada.
Johnny-Wei BaiLunenfeld-Tanenbaum Research Institute, Mount Sinai Hospital, Toronto, Ontario, Canada.
Yuliya LytvynDivision of Nephrology, Department of Medicine, University of Toronto, Toronto, Ontario, Canada.
Geneviève BouletLunenfeld-Tanenbaum Research Institute, Mount Sinai Hospital, Toronto, Ontario, Canada.
Mohammed A FarooqiLunenfeld-Tanenbaum Research Institute, Mount Sinai Hospital, Toronto, Ontario, Canada.
Sam SantiagoJoint Department of Medical Imaging, Division of Cardiothoracic Radiology, University Health Network, Toronto, Ontario, Canada.
Andrej OrszagLunenfeld-Tanenbaum Research Institute, Mount Sinai Hospital, Toronto, Ontario, Canada.
Daniel ScarrLunenfeld-Tanenbaum Research Institute, Mount Sinai Hospital, Toronto, Ontario, Canada.
Alanna WeismanLunenfeld-Tanenbaum Research Institute, Mount Sinai Hospital, Toronto, Ontario, Canada.
Hillary A KeenanResearch Division, Joslin Diabetes Center, Boston, MA.ORCID 0000-0003-4172-5537
Michael H BrentDepartment of Ophthalmology and Vision Sciences, Department of Medicine, University of Toronto, Toronto, Ontario, Canada.
Narinder PaulJoint Department of Medical Imaging, Division of Cardiothoracic Radiology, University Health Network, Toronto, Ontario, Canada.
Vera BrilThe Ellen and Martin Prosserman Centre for Neuromuscular Diseases, Krembil Neuroscience Centre, Division of Neurology, Department of Medicine, University Health Network, University of Toronto, Toronto, Ontario, Canada.ORCID 0000-0002-5805-4883
Bruce A PerkinsDivision of Endocrinology and Metabolism, Department of Medicine, University of Toronto, Toronto, Ontario, Canada.ORCID 0000-0002-5885-0046
David Z I CherneyDivision of Nephrology, Department of Medicine, University of Toronto, Toronto, Ontario, Canada.ORCID 0000-0003-4164-0429
Mount Sinai Hospital · CAUniversity Health Network · CAUniversity of Toronto · CAJoslin Diabetes Center · USSunnybrook Health Science Centre · CAUniversity of Colorado Anschutz Medical Campus · US

Funding

Training Program in Diabetes ResearchT32DK063687 · NIDDK · UNIVERSITY OF COLORADO DENVER · PI Andrea Steck · 2002 to 2026
$5.2M
Renal HEIR Study: Renal Hemodynamics, Energetics and Insulin Resistance in Youth Onset Type 2 Diabetes StudyK23DK116720 · NIDDK · UNIVERSITY OF COLORADO DENVER · PI BJORNSTAD, PETTER · 2018 to 2022
$963k
NIDDK NIH HHS K23 DK116720NIDDK NIH HHS T32 DK063687
6 · The paper itself

Abstract

objectiveType 1 diabetes carries a significant risk for cardiovascular mortality, but it is unclear how atherosclerosis associates with microvascular complications. We aimed to determine the relationships between atherosclerotic burden and neuropathy, retinopathy, and diabetic kidney disease (DKD) in adults with a ≥50-year history of type 1 diabetes. RESEARCH DESIGN AND

methodsAdults with type 1 diabetes (

resultsCAC scores were higher in participants with type 1 diabetes (median Agatston score 1,000 [interquartile range = 222, 2,373] AU vs. 1 [0.75] AU in comparators,

conclusionsThe presence of high CAC in adults with longstanding type 1 diabetes was associated with large nerve fiber neuropathy and retinopathy but not with renal hemodynamic function, suggesting that neuropathy, retinopathy, and macrovascular calcification share common risk factors.

Indexed as

AgedAtherosclerosisCanadaCase-Control StudiesCohort StudiesCoronary Artery DiseaseDiabetes Mellitus, Type 1Diabetic AngiopathiesDiabetic NephropathiesFemaleHumansLongevityMaleMiddle AgedRisk Factors

Identifiers

PMID30275283
PMCPMC6245210
OpenAlexW2895369821

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.