Evidence map›Paper›PMID 30275278›Full record

ArticleJournal of bacteriology2018

The Manganese-Dependent Pyruvate Kinase PykM Is Required for Wild-Type Glucose Utilization by Brucella abortus 2308 and Its Virulence in C57BL/6 Mice.

Joshua E Pitzer, Tonya N Zeczycki, John E Baumgartner, Daniel W Martin, R Martin Roop

Open access · bronzeAbstract read
In one paragraph

Article in Journal of bacteriology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
1.1field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 10 citations in OpenAlex.

  1. Ability ofMicroorganisms · 2026
    Article
  2. Glucose uptake is essential forInfection and immunity · 2025
    Article
  3. Acta biochimica et biophysica Sinica · 2024
    Article
  4. Nramp: Deprive and conquer?Frontiers in cell and developmental biology · 2022
    Article
  5. Uncovering the Hidden Credentials ofMicrobiology and molecular biology reviews : MMBR · 2021
    Review
  6. Article
  7. Article
  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Joshua E PitzerDepartment of Microbiology and Immunology, Brody School of Medicine, East Carolina University, Greenville, North Carolina, USA.
Tonya N ZeczyckiDepartment of Biochemistry and Molecular Biology, Brody School of Medicine, East Carolina University, Greenville, North Carolina, USA.
John E BaumgartnerDepartment of Microbiology and Immunology, Brody School of Medicine, East Carolina University, Greenville, North Carolina, USA.
Daniel W MartinDepartment of Microbiology and Immunology, Brody School of Medicine, East Carolina University, Greenville, North Carolina, USA.
R Martin RoopDepartment of Microbiology and Immunology, Brody School of Medicine, East Carolina University, Greenville, North Carolina, USA roopr@ecu.edu.
East Carolina University · US

Funding

Manganese transport and virulence in BrucellaR21AI112745 · NIAID · EAST CAROLINA UNIVERSITY · PI ROOP, ROY M · 2014 to 2015
$402k
NIAID NIH HHS R21 AI112745
6 · The paper itself

Abstract

Pyruvate kinase plays a central role in glucose catabolism in bacteria, and efficient utilization of this hexose has been linked to the virulence of

Indexed as

AnimalsBacterial ProteinsBrucella abortusBrucellosisGlucoseManganeseMiceMice, Inbred C57BLMutationPhosphotransferasesPyruvate, Orthophosphate DikinaseVirulence FactorsBacterial ProteinsGlucoseManganesePhosphotransferasesPyruvate, Orthophosphate DikinaseVirulence FactorsBrucellaglucose catabolismmanganesepyruvate kinase

Identifiers

PMID30275278
PMCPMC6256021
OpenAlexW2893350443

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.