Evidence map›Paper›PMID 30275267›Full record

ArticleThe EMBO journal2019

Alpha-ketoglutarate: a "magic" metabolite in early germ cell development.

Vivian Lu, Michael A Teitell

Abstract readComment
In one paragraph

Article in The EMBO journal, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Metabolic transitions define spermatogonial stem cell maturation.Human reproduction (Oxford, England) · 2022
    Pooled it
  2. Review
  3. ImprovingJournal of biomedical research · 2025
    Article
  4. Article
  5. Article
  6. Article
  7. Unique metabolic phenotype and its transition during maturation of juvenile male germ cells.FASEB journal : official publication of the Federation of American Societies for Experimental Biology · 2021
    Article
  8. Review
  9. Article
  10. Glutamine reliance in cell metabolism.Experimental & molecular medicine · 2020
    Review
  11. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

2 authors.

Vivian LuDepartment of Molecular and Medical Pharmacology, UCLA, Los Angeles, CA, USA.
Michael A TeitellDepartment of Pathology and Laboratory Medicine, UCLA, Los Angeles, CA, USA.

Funding

Reverse Mitochondrial Genetics Enabled by BlastR01GM114188 · NIGMS · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI CHIOU, PEI-YU, TEITELL, MICHAEL A · 2015 to 2018
$1.9M
Role of pH on Lineage Fate during Pluripotent Stem Cell DifferentiationF31HD097960 · NICHD · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI LU, VIVIAN · 2019 to 2021
$112k
NICHD NIH HHS F31 HD097960NIGMS NIH HHS R01 GM114188
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Germ CellsKetoglutaric AcidsCell DifferentiationKetoglutaric Acids

Identifiers

PMID30275267
PMCPMC6315287

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.