Evidence map›Paper›PMID 30275248›Full record

ArticlePediatrics2018

Obesity and Endocrine Management of the Patient With Duchenne Muscular Dystrophy.

David R Weber, Stasia Hadjiyannakis, Hugh J McMillan, Garey Noritz, Leanne M Ward

Open access · bronzeAbstract read
In one paragraph

Article in Pediatrics, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 33 papers.

0numbers the graph read from it
0cells of the map it votes in
33citing papers in PubMed
1.8field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

33 citing papers in PubMed, 62 citations in OpenAlex.

  1. Trial
  2. Trial
  3. Review
  4. Article
  5. Article
  6. Article
  7. Article
  8. Review
  9. Article
  10. Article
  11. Article
  12. Approach to the Pediatric Patient With Glucocorticoid-Induced Osteoporosis.The Journal of clinical endocrinology and metabolism · 2025
    Article
  13. Article
  14. Article
  15. Article
  16. Article
  17. Article
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

David R WeberGolisano Children's Hospital, School of Medicine and Dentistry, University of Rochester, Rochester, New York.
Stasia HadjiyannakisDepartment of Pediatrics, Children's Hospital of Eastern Ontario, University of Ottawa, Ottawa, Ontario, Canada; and.
Hugh J McMillanDepartment of Pediatrics, Children's Hospital of Eastern Ontario, University of Ottawa, Ottawa, Ontario, Canada; and.
Garey NoritzNationwide Children's Hospital, The Ohio State University, Columbus, Ohio.
Leanne M WardDepartment of Pediatrics, Children's Hospital of Eastern Ontario, University of Ottawa, Ottawa, Ontario, Canada; and lward@cheo.on.ca.
Golisano Children's Hospital · USNationwide Children's Hospital · US

Funding

Translational Molecular Pediatric ResearchK12HD068373 · NICHD · UNIVERSITY OF ROCHESTER · PI SCHOR, NINA F · 2011 to 2015
$2.0M
Investigation of Hypercalciuria as a Cause of Impaired Bone Mineral Accrual in Type 1 DiabetesK23DK114477 · NIDDK · UNIVERSITY OF ROCHESTER · PI WEBER, DAVID R · 2017 to 2019
$573k
CIHRNICHD NIH HHS K12 HD068373NIDDK NIH HHS K23 DK114477OSTLTS CDC HHS U38 OT000167
6 · The paper itself

Abstract

Duchenne muscular dystrophy (DMD) is associated with an increased risk of endocrine complications due to the effects of prolonged glucocorticoid therapy as well as progressive muscle weakness. Categories of complications include obesity and its comorbidities, short stature, pubertal delay, and adrenal insufficiency. Obesity prevention is important for long-term management of patients with DMD. Preventing glucocorticoid-induced weight gain fosters patient mobility, ease of transfer, and reduces sleep-disordered breathing. Metabolic complications from obesity (glucose intolerance, dyslipidemia) also can be avoided. Short stature and pubertal delay may negatively affect self-esteem and peer relationships, and careful monitoring of growth and pubertal development can allow anticipatory counseling. Adrenal insufficiency, a potentially life-threatening complication associated with prolonged glucocorticoid use, must be recognized so as to allow prompt treatment. In this article, we provide a summary of current guidance to ensure comprehensive endocrine management is followed in patients with DMD.

Indexed as

Endocrine System DiseasesGlucocorticoidsHumansMuscular Dystrophy, DuchenneObesityPractice Guidelines as TopicGlucocorticoids

Identifiers

PMID30275248
PMCPMC6460463
OpenAlexW2892513209

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.