Evidence map›Paper›PMID 30275008›Full record

ArticleInfection and immunity2018

Tracking Anti-

Irvin Oh, Gowrishankar Muthukrishnan, Mark J Ninomiya, James D Brodell, Benjamin L Smith, Charles C Lee, Steven R Gill, Christopher A Beck, Edward M Schwarz, John L Daiss

Registry-linked trialOpen access · bronzeAbstract read
In one paragraph

Article in Infection and immunity, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT04897971 (Use of MENSA to Improve the Diagnosis of Causative Infectious Agent and Monitor Infection Recovery in Orthopedic Spine Infection), which is not on this map. Cited by 29 papers.

0numbers the graph read from it
0cells of the map it votes in
29citing papers in PubMed
4.4field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT04897971 unknown statusnot on this mapstarted 2021, after this paper: background citation

Use of MENSA to Improve the Diagnosis of Causative Infectious Agent and Monitor Infection Recovery in Orthopedic Spine Infection

TypeobservationalSponsorUniversity of Colorado, DenverRan2021 to 2026Enrolled200ConditionsStaphylococcus Aureus Infection, Surgical Site Infection, Orthopedic Procedures, SpineArmsMedium enriched for newly synthesized antibodies in spine infection
3 · Its place in the literature

Who cites it

29 citing papers in PubMed, 39 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. Transcriptomic identification of genes expressed in invasiveFrontiers in cellular and infection microbiology · 2023
    Article
  7. Observational
  8. Low albumin level is more strongly associated with adverse outcomes and Staphylococcus aureus infection than hemoglobin A1C or smoking tobacco.Journal of orthopaedic research : official publication of the Orthopaedic Research Society · 2022
    Article
  9. Article
  10. Article
  11. Review
  12. Comparative study of culture, next-generation sequencing, and immunoassay for identification of pathogen in diabetic foot ulcer.Journal of orthopaedic research : official publication of the Orthopaedic Research Society · 2021
    Observational
  13. Article
  14. Serum antibodies against Staphylococcus aureus can prognose treatment success in patients with bone infections.Journal of orthopaedic research : official publication of the Orthopaedic Research Society · 2021
    Article
  15. Article
  16. Article
  17. Article
  18. Distinct expression trend of signature antigens of Staphylococcus aureus osteomyelitis correlated with clinical outcomes.Journal of orthopaedic research : official publication of the Orthopaedic Research Society · 2021
    Article
  19. Bacterial toxins in musculoskeletal infections.Journal of orthopaedic research : official publication of the Orthopaedic Research Society · 2021
    Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 2 institutions in 1 country.

Irvin Oh *Center for Musculoskeletal Research and Department of Orthopaedics, University of Rochester Medical Center, Rochester, New York, USA.
Gowrishankar Muthukrishnan *Center for Musculoskeletal Research and Department of Orthopaedics, University of Rochester Medical Center, Rochester, New York, USA.ORCID 0000-0001-7521-6154
Mark J NinomiyaCenter for Musculoskeletal Research and Department of Orthopaedics, University of Rochester Medical Center, Rochester, New York, USA.
James D BrodellCenter for Musculoskeletal Research and Department of Orthopaedics, University of Rochester Medical Center, Rochester, New York, USA.
Benjamin L SmithCenter for Musculoskeletal Research and Department of Orthopaedics, University of Rochester Medical Center, Rochester, New York, USA.
Charles C LeeCenter for Musculoskeletal Research and Department of Orthopaedics, University of Rochester Medical Center, Rochester, New York, USA.
Steven R GillDepartment of Microbiology and Immunology, School of Medicine and Dentistry, University of Rochester, Rochester, New York, USA.
Christopher A BeckCenter for Musculoskeletal Research and Department of Orthopaedics, University of Rochester Medical Center, Rochester, New York, USA.
Edward M SchwarzCenter for Musculoskeletal Research and Department of Orthopaedics, University of Rochester Medical Center, Rochester, New York, USA.
John L DaissCenter for Musculoskeletal Research and Department of Orthopaedics, University of Rochester Medical Center, Rochester, New York, USA john_daiss@urmc.rochester.edu.
University of Rochester Medical Center · USUniversity of Rochester · US

Funding

Project 2: Defining the Protective vs. Susceptible Immune Proteome of S. aureus OsteomyelitisP50AR072000 · NIAMS · UNIVERSITY OF ROCHESTER · PI Edward M. Schwarz · 2017 to 2026
$13.6M
Diagnosis of early Staphylococcus aureus infections using circulating plasmablastsR21AI119646 · NIAID · UNIVERSITY OF ROCHESTER · PI DAISS, JOHN LINFORTH · 2016 to 2017
$422k
Pathogen-specific and Prognosis of S. aureus infection in Orthopaedic SurgeryR21AR074571 · NIAMS · YALE UNIVERSITY · PI OH, IRVIN · 2018 to 2019
$376k
NIAID NIH HHS R21 AI119646NIAMS NIH HHS P50 AR072000NIAMS NIH HHS R21 AR074571
6 · The paper itself

Abstract

Management of foot salvage therapy (FST) for diabetic foot infections (DFI) is challenging due to the absence of reliable diagnostics to identify the etiologic agent and prognostics to justify aggressive treatments. As

Indexed as

Immunity, HumoralSalvage TherapyAgedAntibodies, BacterialDiabetic FootFemaleHumansImmunoassayImmunoglobulin GLeukocytes, MononuclearMaleMiddle AgedPrognosisRNA, Ribosomal, 16SROC CurveStaphylococcal InfectionsAntibodies, BacterialImmunoglobulin GRNA, Ribosomal, 16Sdiabetesdiabetic foot infectionsdiagnosticsimmunoassaysplasmablastsStaphylococcus aureus

Identifiers

PMID30275008
PMCPMC6246899
OpenAlexW2895073707

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.