Evidence map›Paper›PMID 30274604›Full record

ReviewTrends in neurosciences2018

Inhibitory Interneurons Regulate Temporal Precision and Correlations in Cortical Circuits.

Jessica A Cardin

Abstract readReview
In one paragraph

Review in Trends in neurosciences, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 143 papers.

0numbers the graph read from it
0cells of the map it votes in
143citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

143 citing papers in PubMed.

  1. Excitatory and inhibitory networks diverge following early blindness.Cerebral cortex (New York, N.Y. : 1991) · 2026
    Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Review
  8. Review
  9. Article
  10. Subthreshold Kir and IBiological research · 2026
    Article
  11. Article
  12. Article
  13. Article
  14. Article
  15. Article
  16. Cell-type-resolvedbioRxiv : the preprint server for biology · 2025
    Article
  17. Article
  18. Article
  19. Article
  20. Neural Circuit Mapping and Neurotherapy-Based Strategies.Cellular and molecular neurobiology · 2025
    Review

83 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

1 author.

Jessica A CardinDepartment of Neuroscience, Yale University, New Haven, CT 06520, USA; Kavli Institute for Neuroscience, Yale University, New Haven, CT 06520, USA. Electronic address: jess.cardin@yale.edu.

Funding

Yale Core Grant for Vision ResearchP30EY026878 · NEI · YALE UNIVERSITY · PI In-Jung Kim · 2016 to 2026
$7.1M
Inhibitory regulation of cortical visual processingR01EY022951 · NEI · YALE UNIVERSITY · PI CARDIN, JESSICA A · 2013 to 2025
$4.0M
GABAergic contributions to neural circuit deficits in schizophreniaR01MH102365 · NIMH · YALE UNIVERSITY · PI CARDIN, JESSICA A · 2014 to 2018
$2.1M
Role of GABAergic interneurons in developmental dysregulation of cortical functionR01MH113852 · NIMH · YALE UNIVERSITY · PI CARDIN, JESSICA A, HIGLEY, MICHAEL JAMES · 2017 to 2021
$2.1M
NEI NIH HHS P30 EY026878NEI NIH HHS R01 EY022951NIMH NIH HHS R01 MH102365NIMH NIH HHS R01 MH113852
6 · The paper itself

Abstract

GABAergic interneurons, which are highly diverse, have long been thought to contribute to the timing of neural activity as well as to the generation and shaping of brain rhythms. GABAergic activity is crucial not only for entrainment of oscillatory activity across a neural population, but also for precise regulation of the timing of action potentials and the suppression of slow-timescale correlations. The diversity of inhibition provides the potential for flexible regulation of patterned activity, but also poses a challenge to identifying the elements of excitatory-inhibitory interactions underlying network engagement. This review highlights the key roles of inhibitory interneurons in spike correlations and brain rhythms, describes several scales on which GABAergic inhibition regulates timing in neural networks, and identifies potential consequences of inhibitory dysfunction.

Indexed as

Action PotentialsAnimalsHumansInterneuronsModels, NeurologicalNerve NetNeural InhibitionSynapsesinterneuronoscillationparvalbuminsomatostatinsynchronyVIP

Identifiers

PMID30274604
PMCPMC6173199

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.