ReviewTrends in neurosciences2018
Hormonal Cycles, Brain Network Connectivity, and Windows of Vulnerability to Affective Disorder.
Review in Trends in neurosciences, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 41 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
41 citing papers in PubMed.
- Intrinsic network static and dynamic functional connectivity associated with induced affect.Social cognitive and affective neuroscience · 2026Article
- Menstrual cycle variations in stress vulnerability and sociability relate to mental health symptoms and libido.npj women's health · 2026Article
- Dynamic brain mechanisms supporting salient memories under cortisol.Science advances · 2025Article
- Cross-cultural validation of the Chinese version of Disorder-Specific Intolerance of Uncertainty (DSIU): psychometric properties in female college students with premenstrual syndrome (PMS).BMC psychiatry · 2025Article
- Posttraumatic Stress Disorder-Related Differences in Neural Connectivity Among Female Trauma Survivors.Biological psychiatry global open science · 2025Article
- Two paradoxes in women's well-being.Science advances · 2025Review
- Review
- Temporal dissociation between local and global functional adaptations of the maternal brain to childbirth: a longitudinal assessment.Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology · 2024Article
- PTSD-related differences in resting-state functional connectivity and associations with sex hormones.medRxiv : the preprint server for health sciences · 2024Article
- Depression in adolescence and young adulthood: the difficulty to integrate motivational/emotional systems.Frontiers in psychology · 2024Review
- Looking Back to Move Forward: Research in Stress, Behavior, and Immune Function.Neuroimmunomodulation · 2024Review
- Neuroscience Needs Network Science.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2023Article
- Neuroscience needs Network Science.ArXiv · 2023Article
- Progesterone and Its Metabolites Play a Beneficial Role in Affect Regulation in the Female Brain.Pharmaceuticals (Basel, Switzerland) · 2023Review
- Article
- Sex-Determined Alteration of Frontal Electroencephalographic (EEG) Activity in Social Presence.Life (Basel, Switzerland) · 2023Article
- Examining a window of vulnerability for affective symptoms in the mid-luteal phase of the menstrual cycle.Psychoneuroendocrinology · 2023Article
- The longitudinal predictive effect of self-reported frequency of premenstrual syndrome on depression: Findings from the Australian Longitudinal Study on Women's Health.Frontiers in public health · 2023Article
- Opposite effects of estradiol and progesterone on woman's disgust processing.Frontiers in psychiatry · 2023Article
- Effect of transcranial direct current stimulation on the functionality of 40 Hz auditory steady state response brain network: graph theory approach.Frontiers in psychiatry · 2023Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors.
Funding
Abstract
The rate of affective disorder is substantially higher in women than in men, and considerable evidence points to the actions of ovarian hormones in mediating this disparity. In this Opinion, we discuss the hypothesis that cyclic changes in ovarian hormone levels produce cyclic alterations in connectivity between the intrinsic networks of the brain. These alterations produce specific temporal windows within the menstrual cycle when internetwork connectivity is increased, associated with increased stress reactivity and better memory for unpleasant, arousing events, leading to increased negative mood and susceptibility to affective disorder. Our windows of vulnerability model offers insights for both treatment of affective disorder and research on sex differences in the brain.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.