Evidence map›Paper›PMID 30274505›Full record

ArticleKorean journal of pediatrics2018

Oral findings and its association with prenatal and perinatal factors in newborns.

Brenda Perez-Aguirre, Uriel Soto-Barreras, Juan Pablo Loyola-Rodriguez, Juan Francisco Reyes-Macias, Miguel Angel Santos-Diaz, Alejandra Loyola-Leyva, Obed Garcia-Cortes

Open access · diamondAbstract read
In one paragraph

Article in Korean journal of pediatrics, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed, 1 pooled it
5.1field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 1 synthesis or guideline pooled it, 26 citations in OpenAlex.

  1. Pooled it
  2. Oral inclusion cysts: a prospective cohort study on distribution, associated factors and prognosis in the first year of life.European archives of paediatric dentistry : official journal of the European Academy of Paediatric Dentistry · 2026
    Article
  3. Article
  4. Gum Lesions in Newborn Infant.Oman medical journal · 2025
    Article
  5. Article
  6. Article
  7. Identification of oral cavity abnormalities in pre-term and full-term newborns: a cross-sectional and comparative study.European archives of paediatric dentistry : official journal of the European Academy of Paediatric Dentistry · 2020
    Article
  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 1 country.

Brenda Perez-AguirreFaculty of Dentistry at Chihuahua University, Chihuahua, México.
Uriel Soto-BarrerasFaculty of Dentistry at Chihuahua University, Chihuahua, México.
Juan Pablo Loyola-RodriguezEscuela Superior de Odontología y Doctorado en Ciencias Biomédicas, Universidad Autónoma de Guerrero, Acapulco, México.
Juan Francisco Reyes-MaciasFaculty of Dentistry at San Luis Potosi University, San Luis Potosi, México.
Miguel Angel Santos-DiazFaculty of Dentistry at San Luis Potosi University, San Luis Potosi, México.
Alejandra Loyola-LeyvaDoctorado en Ciencias Biomédicas Básicas, San Luis Potosi University, San Luis Potosi, México.
Obed Garcia-CortesFaculty of Dentistry at San Luis Potosi University, San Luis Potosi, México.
Polytechnic University of San Luis Potosí · MXAutonomous University of Chihuahua · MXUniversidad Autónoma de Guerrero · MX

Funding

Consejo Nacional de Ciencia y Tecnología 157329Consejo Nacional de Ciencia y Tecnología 254422
6 · The paper itself

Abstract

purposeThis study aimed to determine the frequency of abnormalities in the newborn oral cavity and to evaluate the association with prenatal and perinatal factors.

methodsThis cross-sectional study evaluated 2,216 newborns. Oral findings were assessed in the first 24 hours of life using visual examination. Sex, weight, length, gestational age, and medical disorders at birth were recorded. Maternal demographic and medical information was also obtained.

resultsThe most common oral findings were Bohn's nodules, Epstein's pearls, and dental lamina cysts. Other intraoral findings included odontogenic cysts, ankyloglossia, and natal teeth, among others. In logistic regression analyses, folic acid consumption during pregnancy was significantly associated with Bohn's nodules (odds ratio [OR], 1.79; 95% confidence interval [CI], 1.23-2.55; P=0.002), Epstein's pearls (OR, 1.63; 95% CI, 1.14-2.33; P=0.007), and dental lamina cysts (OR, 1.45; 95% CI, 1.02-2.05; P=0.038). Moreover, preterm births were negatively associated with prevalence of Bohn's nodules (OR, 0.63; 95% CI, 0.50-0.80; P≤0.0001). Comparison between newborns with and without oral inclusion cysts showed that maternal folic acid and iron intake were significantly different (P<0.05).

conclusionMaternal folic acid and iron intake were associated with the prevalence of oral inclusion cysts.

Indexed as

Gingival pathologyInfantMouth abnormalitiesNewborn

Identifiers

PMID30274505
PMCPMC6172521
OpenAlexW2891673178

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.