Evidence map›Paper›PMID 30274491›Full record

ArticleTropical medicine and infectious disease2018

Diagnostic Accuracy of the InBios Scrub Typhus Detect™ ELISA for the Detection of IgM Antibodies in Chittagong, Bangladesh.

Stuart D Blacksell, Hugh W F Kingston, Ampai Tanganuchitcharnchai, Meghna Phanichkrivalkosil, Mosharraf Hossain, Amir Hossain, Aniruddha Ghose, Stije J Leopold, Arjen M Dondorp, Nicholas P J Day and 1 more

Registry-linked trialOpen access · goldAbstract read
In one paragraph

Article in Tropical medicine and infectious disease, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT03847870 (Background Seroprevalence of Rickettsial Infections in Myanmar), which is not on this map. Cited by 17 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed, 1 pooled it
4.1field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT03847870 completednot on this mapstarted 2019, after this paper: background citation

Background Seroprevalence of Rickettsial Infections in Myanmar

TypeobservationalSponsorMyanmar Oxford Clinical Research UnitRan2019 to 2019Enrolled700ConditionsRickettsiae InfectionsArmsMORU in-house ELISA test followed by IFA if positive
3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 1 synthesis or guideline pooled it, 31 citations in OpenAlex.

  1. Pooled it
  2. Imaging in scrub typhus - a pictorial review.Abdominal radiology (New York) · 2026
    Review
  3. Review
  4. Article
  5. Article
  6. Scrub typhus with hemorrhagic stroke: a case report.Journal of medical case reports · 2024
    Article
  7. Scrub typhus, a salient threat: Needs attention.PLoS neglected tropical diseases · 2023
    Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Article
  13. Article
  14. Review
  15. Observational
  16. Observational
  17. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 3 institutions in 4 countries.

Stuart D BlacksellMahidol-Oxford Tropical Medicine Research Unit, Faculty of Tropical Medicine, Mahidol University, 420/6 Rajvithee Road, Bangkok 10400, Thailand. Stuart@tropmedres.ac.ORCID 0000-0001-6576-726X
Hugh W F KingstonMahidol-Oxford Tropical Medicine Research Unit, Faculty of Tropical Medicine, Mahidol University, 420/6 Rajvithee Road, Bangkok 10400, Thailand. hwfkingston@googlemail.com.
Ampai TanganuchitcharnchaiMahidol-Oxford Tropical Medicine Research Unit, Faculty of Tropical Medicine, Mahidol University, 420/6 Rajvithee Road, Bangkok 10400, Thailand. ampai@tropmedres.ac.
Meghna PhanichkrivalkosilMahidol-Oxford Tropical Medicine Research Unit, Faculty of Tropical Medicine, Mahidol University, 420/6 Rajvithee Road, Bangkok 10400, Thailand. meghnakosil@hotmail.com.
Mosharraf HossainChittagong Medical College Hospital, Chittagong, Bangladesh. mosharraf144@gmail.com.
Amir HossainChittagong Medical College Hospital, Chittagong, Bangladesh. amir_hossain_ctg@yahoo.com.
Aniruddha GhoseChittagong Medical College Hospital, Chittagong, Bangladesh. anrdghs@yahoo.com.
Stije J LeopoldMahidol-Oxford Tropical Medicine Research Unit, Faculty of Tropical Medicine, Mahidol University, 420/6 Rajvithee Road, Bangkok 10400, Thailand. Stije@tropmedres.ac.ORCID 0000-0002-0482-5689
Arjen M DondorpMahidol-Oxford Tropical Medicine Research Unit, Faculty of Tropical Medicine, Mahidol University, 420/6 Rajvithee Road, Bangkok 10400, Thailand. arjen@tropmedres.ac.
Nicholas P J DayMahidol-Oxford Tropical Medicine Research Unit, Faculty of Tropical Medicine, Mahidol University, 420/6 Rajvithee Road, Bangkok 10400, Thailand. nickd@tropmedres.ac.
Daniel H ParisMahidol-Oxford Tropical Medicine Research Unit, Faculty of Tropical Medicine, Mahidol University, 420/6 Rajvithee Road, Bangkok 10400, Thailand. daniel.paris@swisstph.ch.ORCID 0000-0003-4743-5987
Mahidol University · THChittagong Medical College · BDSwiss Tropical and Public Health Institute · CH

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Here we estimated the accuracy of the InBios Scrub Typhus Detect™ immunoglobulin M (IgM) ELISA to determine the optimal optical density (OD) cut-off values for the diagnosis of scrub typhus. Patients with undifferentiated febrile illness from Chittagong, Bangladesh, provided samples for reference testing using (i) qPCR using the

Indexed as

BangladeshdiagnosisELISAscrub typhus

Identifiers

PMID30274491
PMCPMC6160969
OpenAlexW2889319541

What OpenQuestion holds

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.