ArticleTropical medicine and infectious disease2018
Translational Venomics: Third-Generation Antivenomics of Anti-Siamese Russell's Viper, Daboia siamensis, Antivenom Manufactured in Taiwan CDC's Vaccine Center.
Article in Tropical medicine and infectious disease, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
22 citing papers in PubMed, 1 synthesis or guideline pooled it, 31 citations in OpenAlex.
- Antivenom preclinical efficacy testing against Asian snakes and their availability in Asia: A systematic review.PloS one · 2023Pooled it
- Proteomic diversity of Russell's viper venom: exploring PLA2 isoforms, pharmacological effects, and inhibitory approaches.Archives of toxicology · 2024Review
- Isolation and Pharmacological Characterisation of Pre-Synaptic Neurotoxins from Thai and Javanese Russell's Viper (Toxins · 2024Article
- Article
- Incidence and Risk Factors for Wound Infections after Trimeresurus stejnegeri Snakebites in Taiwan.The American journal of tropical medicine and hygiene · 2024Article
- Venom-gland transcriptomics of the Malayan pit viper (Heliyon · 2023Article
- In Vitro Efficacy of Antivenom and Varespladib in Neutralising Chinese Russell's Viper (Toxins · 2023Article
- Identification of Daboia siamensis venome using integrated multi-omics data.Scientific reports · 2022Article
- In Vitro Toxicity of Chinese Russell's Viper (Toxins · 2022Article
- Development of a Monoclonal scFv against Cytotoxin to Neutralize Cytolytic Activity Induced byToxins · 2022Article
- Comparative compositional and functional venomic profiles among venom specimens from juvenile, subadult and adult Russell's viper (The journal of venomous animals and toxins including tropical diseases · 2022Article
- A Genus-Wide Bioactivity Analysis ofInternational journal of molecular sciences · 2021Article
- Venom-gland transcriptomic, venomic, and antivenomic profiles of the spine-bellied sea snake (Hydrophis curtus) from the South China Sea.BMC genomics · 2021Article
- Article
- Old World Vipers-A Review about Snake Venom Proteomics of Viperinae and Their Variations.Toxins · 2021Review
- Antivenomics and in vivo preclinical efficacy of six Latin American antivenoms towards south-western Colombian Bothrops asper lineage venoms.PLoS neglected tropical diseases · 2021Article
- Collocation of avian and mammal antibodies to develop a rapid and sensitive diagnostic tool for Russell's Vipers Snakebite.PLoS neglected tropical diseases · 2020Article
- Toxinology provides multidirectional and multidimensional opportunities: A personal perspective.Toxicon: X · 2020Article
- Dagestan blunt-nosed viper,Toxicon: X · 2020Article
- Venomics and antivenomics of the poorly studied Brazil's lancehead,The journal of venomous animals and toxins including tropical diseases · 2020Article
Corrections and comments
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Authors and funding
6 authors at 2 institutions in 2 countries.
Funding
Abstract
The venom proteome of Siamese Russell's viper from Taiwan, alongside complementary in vivo lethality neutralization assay and in vitro third-generation antivenomics assessment of the preclinical efficacy of the homologous antivenom manufactured in Taiwan CDC's Vaccine Center, are here reported. Taiwanese Russell's viper venom proteome comprised 25 distinct gene products, with the heterodimeric PLA₂ viperotoxin-F representing the most abundant toxin (47.5% of total venom proteome). Coagulation FV-activating serine proteinase (RVV-V, 14%), the PIV-SVMP activator of FX (RVV-FX, 8.5%), and less abundant toxins from nine protein families, make up its venom proteome. Venom composition-pathology correlations of
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.