Evidence map›Paper›PMID 30274441›Full record

ReviewTropical medicine and infectious disease2018

First Aid and Pre-Hospital Management of Venomous Snakebites.

Jennifer Parker-Cote, William J Meggs

Registry-linked trialOpen access · goldAbstract readReview
In one paragraph

Review in Tropical medicine and infectious disease, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT07261982 (Efficacy of Pressure Pad vs Pressure Bandage Immobilisation for Snake Bite First Aid in Healthy Volunteers.), which is not on this map. Cited by 20 papers.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed
2.7field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT07261982 narecruitingnot on this mapstarted 2025, after this paper: background citation

Efficacy of Pressure Pad vs Pressure Bandage Immobilisation for Snake Bite First Aid in Healthy Volunteers.

TypeinterventionalSponsorTownsville University HospitalRan2025 to 2027Enrolled24ConditionsSnake Bites, Snakebite, Snake Envenomation, Snake BiteArmsPressure bandage immobilisation first aid, Pressure pad first aid, Control - no first aid
3 · Its place in the literature

Who cites it

20 citing papers in PubMed, 47 citations in OpenAlex.

  1. Article
  2. Article
  3. Treatment and treatment outcomes of snakebite envenoming in Uganda: a retrospective analysis.Transactions of the Royal Society of Tropical Medicine and Hygiene · 2025
    Article
  4. Review
  5. Vipera Snakebite in Children: A Focus on Europe.Children (Basel, Switzerland) · 2025
    Review
  6. Review
  7. Review
  8. Article
  9. The Chinese guideline for management of snakebites.World journal of emergency medicine · 2024
    Article
  10. Article
  11. Article
  12. Article
  13. Review
  14. Managing snakebite.BMJ (Clinical research ed.) · 2022
    Review
  15. Case Report: Safe Tourniquet Removal in Black Mamba (Dendroaspis polylepis) Bites.The American journal of tropical medicine and hygiene · 2021
    Article
  16. Article
  17. Article
  18. Prehospital Practices and Clinical Profile of the Patients with Snake Envenomation Admitted in a Tertiary Care Hospital: A Case Series.Indian journal of community medicine : official publication of Indian Association of Preventive & Social Medicine
    Article
  19. Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Jennifer Parker-CoteDivision of Toxicology, Department of Emergency Medicine, Brody School of Medicine at East Carolina University, Greenville, NC 27858, USA. parkercotej16@ecu.edu.
William J MeggsDivision of Toxicology, Department of Emergency Medicine, Brody School of Medicine at East Carolina University, Greenville, NC 27858, USA. meggsw@ecu.edu.
East Carolina University · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundAntivenom is the definitive treatment for venomous snakebites, but is expensive and not available in many rural and poorly developed regions. Timely transportation to facilities that stock and administer antivenom may not be available in rural areas with poorly developed emergency medical services. These factors have led to consideration of measures to delay onset of toxicity or alternatives to antivenom therapy.

methodsPubMed searches were conducted for articles on snakebite treatment, or that contained first aid, emergency medical services, tourniquets, pressure immobilization bandages, suction devices, and lymphatic flow inhibitors.

resultsThe reviewed articles describe how venoms spread after a venomous snakebite on an extremity, list the proposed first aid measures for delaying the spread of venoms, and evaluate the scientific studies that support or refute methods of snakebite first aid. The recommendations for field treatment of venomous snakebites will be discussed.

conclusionsThe evidence suggests that pressure immobilization bandages and related strategies are the best interventions to delay onset of systemic toxicity from venomous snakebites but may increase local toxicity for venoms that destroy tissue at the site of the bite, so their use should be individualized to the circumstances and nature of the venom.

Indexed as

emergency medicine servicesfirst aidpressure immobilization bandagessnakebites

Identifiers

PMID30274441
PMCPMC6073535
OpenAlexW2803011615

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.