Evidence map›Paper›PMID 30274422›Full record

ReviewTropical medicine and infectious disease2018

Melioidosis in Malaysia: Incidence, Clinical Challenges, and Advances in Understanding Pathogenesis.

Sheila Nathan, Sylvia Chieng, Paul Vijay Kingsley, Anand Mohan, Yuwana Podin, Mong-How Ooi, Vanitha Mariappan, Kumutha Malar Vellasamy, Jamuna Vadivelu, Sylvia Daim and 1 more

Abstract readReview
In one paragraph

Review in Tropical medicine and infectious disease, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 38 papers.

0numbers the graph read from it
0cells of the map it votes in
38citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

38 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Pathogens (Basel, Switzerland) · 2026
    Article
  6. Article
  7. Stability assessment of whole cell ELISA for Burkholderia pseudomallei antibodies detection.Brazilian journal of microbiology : [publication of the Brazilian Society for Microbiology] · 2025
    Article
  8. Article
  9. Adaptation of anMethodsX · 2025
    Article
  10. Infection and drug resistance · 2025
    Review
  11. Article
  12. Article
  13. Article
  14. Article
  15. Article
  16. Article
  17. A Rare Case of Complicated Sinonasal Meliodosis Mimicking Sinonasal Lymphoproliferative Disease.Indian journal of otolaryngology and head and neck surgery : official publication of the Association of Otolaryngologists of India · 2023
    Article
  18. Article
  19. Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Sheila NathanSchool of Biosciences and Biotechnology, Faculty of Science and Technology, Universiti Kebangsaan Malaysia, Bangi 43600, Malaysia. sheila@ukm.edu.my.ORCID 0000-0002-2132-2346
Sylvia ChiengSchool of Biosciences and Biotechnology, Faculty of Science and Technology, Universiti Kebangsaan Malaysia, Bangi 43600, Malaysia. sylvia@ukm.edu.my.ORCID 0000-0002-6521-6641
Paul Vijay KingsleyEmergency Department, Pantai Hospital Ipoh, 31400 Ipoh, Malaysia. paulkvijay@gmail.com.
Anand MohanDepartment of Paediatrics, Bintulu Hospital, Bintulu 97000, Malaysia. anand_bintulu@yahoo.com.ORCID 0000-0001-6796-9885
Yuwana PodinInstitute of Health and Community Medicine, Universiti Malaysia Sarawak, Kota Samarahan 94300, Malaysia. pyuwana@unimas.my.
Mong-How OoiInstitute of Health and Community Medicine, Universiti Malaysia Sarawak, Kota Samarahan 94300, Malaysia. monghowooi@gmail.com.
Vanitha MariappanDepartment of Medical Microbiology, Faculty of Medicine, University of Malaya, Kuala Lumpur 50603, Malaysia. vanitha.ma@gmail.com.
Kumutha Malar VellasamyDepartment of Medical Microbiology, Faculty of Medicine, University of Malaya, Kuala Lumpur 50603, Malaysia. kumuthamalar@um.edu.my.
Jamuna VadiveluDepartment of Medical Microbiology, Faculty of Medicine, University of Malaya, Kuala Lumpur 50603, Malaysia. jamuna@ummc.edu.my.
Sylvia DaimDepartment of Pathobiology and Medical Diagnostics, Faculty of Medicine and Health Science, Universiti Malaysia Sabah, Kota Kinabalu 88400, Malaysia. sylviadaim@ums.edu.my.
Soon-Hin HowDepartment of Internal Medicine, Kulliyyah of Medicine, International Islamic University Malaysia, Kuantan 25200, Malaysia. how_sh@yahoo.com.

Funding

Ministry of Higher Education Malaysia RACE/b(2)/1246/2015(02Ministry of Higher Education Malaysia UM.C/625/1/HIR/060 (J-20004-73594Ministry of Science, Technology and Innovation Malaysia 02-05-20-SF0006Ministry of Science, Technology and Innovation Malaysia 06-05-16-MB003Universiti Kebangsaan Malaysia DIP-2015-022
6 · The paper itself

Abstract

Malaysia is an endemic hot spot for melioidosis; however, a comprehensive picture of the burden of disease, clinical presentations, and challenges faced in diagnosis and treatment of melioidosis is not available. This review provides a nonexhaustive overview of epidemiological data, clinical studies, risk factors, and mortality rates from available literature and case reports. Clinical patterns of melioidosis are generally consistent with those from South and Southeast Asia in terms of common primary presentations with diabetes as a major risk factor. Early diagnosis and appropriate management of Malaysian patients is a key limiting factor, which needs to be addressed to reduce serious complications and high mortality and recurrence rates. Promoting awareness among the local healthcare personnel is crucial to improving diagnostics and early treatment, as well as educating the Malaysian public on disease symptoms and risk factors. A further matter of urgency is the need to make this a notifiable disease and the establishment of a national melioidosis registry. We also highlight local studies on the causative agent,

Indexed as

bacteriologyBurkholderia pseudomalleiepidemiologyMalaysiamelioidosis

Identifiers

PMID30274422
PMCPMC6136604

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.