ArticleTropical medicine and infectious disease2018
Rickettsial Infections and Q Fever Amongst Febrile Patients in Bhutan.
Article in Tropical medicine and infectious disease, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers, 2 of them syntheses that pooled it.
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Who cites it
11 citing papers in PubMed, 2 syntheses or guidelines pooled it, 21 citations in OpenAlex.
- Prevalence and Risk Factors of Coxiellosis at the Human-Animal-Environment Interface in the South Asian Countries: A Systematic Review and Meta-Analysis.Transboundary and emerging diseases · 2025Pooled it
- Prevalence of malaria and scrub typhus co-infection in febrile patients: a systematic review and meta-analysis.Parasites & vectors · 2021Pooled it
- Genetic Characterization of Orientia tsutsugamushi, Bhutan, 2015.Emerging infectious diseases · 2025Article
- A Review of Rickettsial Diseases Other Than Scrub Typhus in India.Tropical medicine and infectious disease · 2023Review
- A scrub typhus vaccine presents a challenging unmet need.NPJ vaccines · 2023Review
- Molecular detection ofFrontiers in microbiology · 2023Article
- An outbreak investigation of scrub typhus in Nepal: confirmation of local transmission.BMC infectious diseases · 2021Article
- A Brief History of the Major Rickettsioses in the Asia-Australia-Pacific Region: A Capstone Review for the Special Issue ofTropical medicine and infectious disease · 2020Review
- Optimization and Evaluation of a Multiplex Quantitative PCR Assay for Detection of Nucleic Acids in Human Blood Samples from Patients with Spotted Fever Rickettsiosis, Typhus Rickettsiosis, Scrub Typhus, Monocytic Ehrlichiosis, and Granulocytic Anaplasmosis.Journal of clinical microbiology · 2020Article
- Seroprevalence of typhus group rickettsial infections in the north-east region of India.The Indian journal of medical research · 2019Article
- Rickettsial infections of the central nervous system.PLoS neglected tropical diseases · 2019Review
Corrections and comments
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Authors and funding
7 authors at 2 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
There is limited evidence of rickettsial diseases in Bhutan. We explored the contribution of rickettsioses as a cause of undifferentiated febrile illness in patients presenting to 14 Bhutanese hospitals from October 2014 to June 2015. Obvious causes of fever were excluded clinically. Clinico-demographic information and acute blood samples were collected. Samples were tested by immunofluorescence assay (IFA) and qPCR against scrub typhus group (STG), spotted fever group (SFG) and typhus group (TG) rickettsiae, and Q fever (QF). Of the 1044 patients, 539 (51.6%) were female and the mean age was 31.5 years. At least 159 (15.2%) of the patients had evidence of a concurrent rickettsial infection. Of these, 70 (6.7%), 46 (4.4%), 4 (0.4%), and 29 (2.8%) were diagnosed as acute infections with STG, SFG, TG, and QF respectively. Ten (1.0%) patients were seropositive for both SFG and TG. Seven of the 70 STG patients were positive by qPCR. Eschar (
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Registered trials
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