Evidence map›Paper›PMID 30274366›Full record

ArticleInternational journal of molecular sciences2018

Directed Evolution of a Homodimeric Laccase from

Ji Zhang, Fuying Ma, Xiaoyu Zhang, Anli Geng

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in International journal of molecular sciences, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
3.0field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 20 citations in OpenAlex.

  1. Review
  2. Article
  3. Review
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 2 countries.

Ji ZhangKey Laboratory of Molecular Biophysics of MOE, College of Life Science and Technology, Huazhong University of Science and Technology, Wuhan 430074, China. zji5@np.edu.sg.
Fuying MaKey Laboratory of Molecular Biophysics of MOE, College of Life Science and Technology, Huazhong University of Science and Technology, Wuhan 430074, China. mafuying@hust.edu.cn.
Xiaoyu ZhangKey Laboratory of Molecular Biophysics of MOE, College of Life Science and Technology, Huazhong University of Science and Technology, Wuhan 430074, China. zhangxiaoyu@mail.hust.edu.cn.
Anli GengSchool of Life Sciences and Chemical Technology, Ngee Ann Polytechnic, Singapore 599489, Singapore. gan2@np.edu.sg.
Huazhong University of Science and Technology · CNNgee Ann Polytechnic · SG

Funding

Ministry of Education - Singapore MOE2013-TIF-1-G-062
6 · The paper itself

Abstract

Laccases have great potential for industrial applications due to their green catalytic properties and broad substrate specificities, and various studies have attempted to improve the catalytic performance of these enzymes. Here, to the best of our knowledge, we firstly report the directed evolution of a homodimeric laccase from

Indexed as

Directed Molecular EvolutionMutagenesisProtein MultimerizationAmino Acid SequenceBasidiomycotaEnzyme StabilityHydrogen-Ion ConcentrationKineticsLaccaseModels, MolecularTemperatureLaccaseCerrena unicolorenzyme directed evolutionerror-prone PCRhomodimerin vivo assemblylaccaselow-rate mutationprotein modellingα-factor

Identifiers

PMID30274366
PMCPMC6213006
OpenAlexW2893667651

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.