Evidence map›Paper›PMID 30274357›Full record

ArticleInternational journal of molecular sciences2018

Immunogenicity and Protective Activity of a Chimeric Protein Based on the Domain III of the Tick-Borne Encephalitis Virus E Protein and the OmpF Porin of

Nina Sanina, Natalia Chopenko, Andrey Mazeika, Ludmila Davydova, Galina Leonova, Anna Stenkova, Vladimir N Uversky, Eduard Kostetsky

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in International journal of molecular sciences, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.4field-weighted citation impact, top 30% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 3 citations in OpenAlex.

  1. Role of hyperoxic treatment in cancer.Experimental biology and medicine (Maywood, N.J.) · 2020
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 2 countries.

Nina SaninaFar Eastern Federal University, 8 Sukhanova St., Vladivostok 690091, Russia. sanina.nm@dvfu.ru.ORCID 0000-0001-5838-691X
Natalia ChopenkoFar Eastern Federal University, 8 Sukhanova St., Vladivostok 690091, Russia. natali_1389@mail.ru.ORCID 0000-0003-0244-517X
Andrey MazeikaFar Eastern Federal University, 8 Sukhanova St., Vladivostok 690091, Russia. nikandrei@inbox.ru.
Ludmila DavydovaFar Eastern Federal University, 8 Sukhanova St., Vladivostok 690091, Russia. l.vorobushek@mail.ru.
Galina LeonovaSomov Institute of Epidemiology and Microbiology, 1 Selskaya st., Vladivostok 690087, Russia. galinaleon41@gmail.com.
Anna StenkovaFar Eastern Federal University, 8 Sukhanova St., Vladivostok 690091, Russia. stenkova@gmail.com.
Vladimir N UverskyDepartment of Molecular Medicine and USF Health Byrd Alzheimer's Research Institute, Morsani College of Medicine, University of South Florida, 12901 Bruce B. Downs Blvd. MDC07, Tampa, FL 33612, USA. vuversky@health.usf.edu.ORCID 0000-0002-4037-5857
Eduard KostetskyFar Eastern Federal University, 8 Sukhanova St., Vladivostok 690091, Russia. kostetskiy.yeya@dvfu.ru.
Far Eastern Federal University · RUUniversity of South Florida · US

Funding

Russian Science Foundation 15-15-00035-P
6 · The paper itself

Abstract

Tick-borne encephalitis (TBE) is a widespread, dangerous infection. Unfortunately, all attempts to create safe anti-TBE subunit vaccines are still unsuccessful due to their low immunogenicity. The goal of the present work was to investigate the immunogenicity of a recombinant chimeric protein created by the fusion of the EIII protein, comprising domain III and a stem region of the tick-borne encephalitis virus (TBEV) E protein, and the OmpF porin of

Indexed as

AnimalsAntibodiesAntigensEncephalitis Viruses, Tick-BorneGalactolipidsImmunizationMice, Inbred BALB CPorinsProtein DomainsRecombinant Fusion ProteinsViral Envelope ProteinsYersinia pseudotuberculosisAntibodiesAntigensGalactolipidsglycoprotein E, FlavivirusmonogalactosyldiacylglycerolOmpF proteinPorinsRecombinant Fusion ProteinsViral Envelope Proteinsfusion antigenmonogalactosyldiacylglycerolnanoparticulate adjuvantnanoparticulate delivery systemsubunit vaccinesTBEV

Identifiers

PMID30274357
PMCPMC6213927
OpenAlexW2893651686

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.