Trial reportNutrients2018
The Acute Effects of Caffeinated Black Coffee on Cognition and Mood in Healthy Young and Older Adults.
Trial report in Nutrients, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 50 papers, 2 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
50 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- The Impact of Lockdowns on Caffeine Consumption: A Systematic Review of the Evidence.International journal of environmental research and public health · 2022Pooled it
- Acute Effects of Polyphenols on Human Attentional Processes: A Systematic Review and Meta-Analysis.Frontiers in neuroscience · 2021Pooled it
- Comparable improvements in selective, but not sustained, attention in response to a multi-ingredient nootropic formulation when compared with caffeine.European journal of nutrition · 2026Trial
- The cognitive effects of supplementation with sunflower phosphatidyl serine in healthy children aged 8 to 12 years: a randomized controlled trial.Nutrition journal · 2025Trial
- Exploring the acute and chronic effects of a multistrain probiotic supplement on cognitive function and mood in healthy older adults: a randomized controlled trial.The American journal of clinical nutrition · 2025Trial
- Effects of laughter on focus and stress in middle-aged adults: a single-blind, randomized controlled trial.BMC complementary medicine and therapies · 2025Trial
- Concurrent consumption of cocoa flavanols and caffeine does not acutely modulate working memory and attention.European journal of nutrition · 2024Trial
- Mixed Tree Nuts, Cognition, and Gut Microbiota: A 4-Week, Placebo-Controlled, Randomized Crossover Trial in Healthy Nonelderly Adults.The Journal of nutrition · 2023Trial
- Trial
- Effect of a 12-Week Almond-Enriched Diet on Biomarkers of Cognitive Performance, Mood, and Cardiometabolic Health in Older Overweight Adults.Nutrients · 2020Trial
- The Therapeutic Architecture of Chlorogenic Acids: Molecular Mechanisms in Chronic Disease Prevention.Nutrients · 2026Review
- Psychobiological Correlates of Perceived Physical Activity Barriers: Insomnia, Chronotype, and Caffeine Consumption.International journal of environmental research and public health · 2026Article
- Differential Time-of-Day Effects of Caffeine Capsule and Mouth Rinse on Cognitive Performance in Adolescent Male Volleyball Athletes: A Randomized Crossover Investigation.Life (Basel, Switzerland) · 2025Article
- Review
- The association of caffeine consumption with positive affect but not with negative affect changes across the day.Scientific reports · 2025Article
- Comprehensive machine learning assessment of zebrafish behaviour and biochemical markers in response to caffeine exposure.Ecotoxicology (London, England) · 2025Article
- Caffeine as a Modulator in Oncology: Mechanisms of Action and Potential for Adjuvant Therapy.International journal of molecular sciences · 2025Review
- (-)-Epicatechin Rescues Memory Deficits by Activation of Autophagy in a Mouse Model of Tauopathies.MedComm · 2025Article
- Review
- Decoding event-related potentials: single-dose energy dietary supplement acts on earlier brain processes than we thought.Frontiers in neuroinformatics · 2025Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors.
Funding
Abstract
Cognitive and mood benefits of coffee are often attributed to caffeine. However, emerging evidence indicates behavioural effects of non-caffeine components within coffee, suggesting the potential for direct or synergistic effects of these compounds when consumed with caffeine in regular brewed coffee. The current randomised, placebo-controlled, double-blind, counterbalanced-crossover study compared the effects of regular coffee, decaffeinated coffee, and placebo on measures of cognition and mood. Age and sex effects were explored by comparing responses of older (61⁻80 years,
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.