ReviewMarine drugs2018
Antibiotics from Deep-Sea Microorganisms: Current Discoveries and Perspectives.
Review in Marine drugs, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 66 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
66 citing papers in PubMed.
- Global distribution of deep-sea natural products shows environmental and phylogenetic undersampling with potential for biodiscovery.Scientific reports · 2026Article
- Medicinal Plants: A Promising Therapeutic Approach for Addressing Antimicrobial Resistance.International journal of molecular sciences · 2026Review
- Genome Mining of Deep-Sea Cold Seep-Derived Fungus Reveals a Laccase-Fasciclin System Modulating Regioselective Naphthopyranone Dimerization.International journal of molecular sciences · 2026Article
- Multi-Omic Assessment of Microbial Communities and Their Polyketide Biosynthetic Potential Across Abyssal Sediments.Environmental microbiology · 2026Article
- OSMAC guided bioprospecting of Atlantic sponges reveals novel bacterial species and evidence for the antimicrobial thiazole alkaloid agrochelin II.Applied and environmental microbiology · 2026Article
- Lubrication Challenges in Deep-Sea Gear Trans-Missions: A Review of High-Pressure and Low-Temperature Effects.Materials (Basel, Switzerland) · 2026Review
- Genome-Driven Discovery of Anti-MDR Bacterial Heptapeptides from a Cold-Seep-DerivedMolecules (Basel, Switzerland) · 2026Article
- Phyllosphere microbiome: Exploring the unexplored frontiers for precision agricultural and environmental sustainability.World journal of microbiology & biotechnology · 2026Review
- Beyond antibiotics: the expanding horizon of microbial natural products.Frontiers in antibiotics · 2026Review
- Disruption of MRSA Biofilm and Virulence by Deep-Sea Probiotics: Impacts on Energy metabolism and Host Antimicrobial Peptides.Probiotics and antimicrobial proteins · 2025Article
- Strategies Used for the Discovery of New Microbial Metabolites with Antibiotic Activity.Molecules (Basel, Switzerland) · 2025Review
- Fighting Antimicrobial Resistance: Innovative Drugs in Antibacterial Research.Angewandte Chemie (International ed. in English) · 2025Review
- Structurally Diverse New Metabolites from Three Hadal Trench-Derived Microorganisms.ACS omega · 2025Article
- Metabolic Blockade-Based Genome Mining ofMarine drugs · 2025Article
- Exploration of novel bioactive compounds from the microbiome of fish and shellfish as an alternative to replace antibiotic drugs in aquaculture farming.Gut microbiome (Cambridge, England) · 2025Review
- Virucidal and cytotoxic properties of a natural honeybee hives-derived formulation suspended with marine plasma.Frontiers in cellular and infection microbiology · 2025Article
- A Comprehensive Review on Bioactive Molecules and Advanced Microorganism Management Technologies.Current issues in molecular biology · 2024Review
- Environmental Antimicrobial Resistance: Implications for Food Safety and Public Health.Antibiotics (Basel, Switzerland) · 2024Review
- Anthoteibinenes A-E from the Irish Deep-Sea CoralOrganic letters · 2024Article
- A Systemic Review on Fitness and Survival ofIndian journal of microbiology · 2024Review
6 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors.
Funding
Abstract
The increasing emergence of new forms of multidrug resistance among human pathogenic bacteria, coupled with the consequent increase of infectious diseases, urgently requires the discovery and development of novel antimicrobial drugs with new modes of action. Most of the antibiotics currently available on the market were obtained from terrestrial organisms or derived semisynthetically from fermentation products. The isolation of microorganisms from previously unexplored habitats may lead to the discovery of lead structures with antibiotic activity. The deep-sea environment is a unique habitat, and deep-sea microorganisms, because of their adaptation to this extreme environment, have the potential to produce novel secondary metabolites with potent biological activities. This review covers novel antibiotics isolated from deep-sea microorganisms. The chemical classes of the compounds, their bioactivities, and the sources of organisms are outlined. Furthermore, the authors report recent advances in techniques and strategies for the exploitation of deep-sea microorganisms.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.