Evidence map›Paper›PMID 30274229›Full record

ReviewAntioxidants (Basel, Switzerland)2018

Redox Signaling of NADPH Oxidases Regulates Oxidative Stress Responses, Immunity and Aging.

Collin Y Ewald

Open access · goldAbstract readReview
In one paragraph

Review in Antioxidants (Basel, Switzerland), 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 47 papers.

0numbers the graph read from it
0cells of the map it votes in
47citing papers in PubMed
4.4field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

47 citing papers in PubMed, 83 citations in OpenAlex.

  1. Review
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  9. Frontiers in tuberculosis · 2025
    Review
  10. Article
  11. Article
  12. Modeling Host-Pathogen Interactions inInternational journal of molecular sciences · 2024
    Review
  13. Article
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  15. Neuronal MML-1/MXL-2 regulates systemic aging via glutamate transporter and cell nonautonomous autophagic and peroxidase activity.Proceedings of the National Academy of Sciences of the United States of America · 2023
    Article
  16. Article
  17. Article
  18. Article
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  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

1 author at 1 institution in 1 country.

Collin Y EwaldEidgenössische Technische Hochschule (ETH) Zürich, Department of Health Sciences and Technology, Institute of Translational Medicine, 8603 Schwerzenbach-Zürich, Switzerland. collin-ewald@ethz.ch.ORCID 0000-0003-1166-4171
Board of the Swiss Federal Institutes of Technology · CH

Funding

Schweizerischer Nationalfonds zur Förderung der Wissenschaftlichen Forschung PP00P3_163898
6 · The paper itself

Abstract

An accumulating body of evidence suggests that transient or physiological reactive oxygen species (ROS) generated by nicotinamide adenine dinucleotide phosphate (NADPH) oxidases act as a redox signal to re-establish homeostasis. The capacity to re-establish homeostasis progressively declines during aging but is maintained in long-lived animals to promote healthy aging. In the model organism

Indexed as

centenariansextracellular matrixlongevityNOXNrf2SKN-1sulfenylation

Identifiers

PMID30274229
PMCPMC6210377
OpenAlexW2892775161

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.