Evidence map›Paper›PMID 30274179›Full record

ArticleGenes2018

Lysine Acetylation Regulates Alanyl-tRNA Synthetase Activity in

Takuya Umehara, Saori Kosono, Dieter Söll, Koji Tamura

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Genes, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
0.8field-weighted citation impact, top 27% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 12 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. Review
  5. Article
  6. Review
  7. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 3 institutions in 2 countries.

Takuya UmeharaBiotechnology Research Center, The University of Tokyo, Tokyo 113-8657, Japan. utumehara@mail.ecc.u-tokyo.ac.jp.
Saori KosonoBiotechnology Research Center, The University of Tokyo, Tokyo 113-8657, Japan. uskos@mail.ecc.u-tokyo.ac.jp.
Dieter SöllDepartment of Molecular Biophysics and Biochemistry, Yale University, New Haven, CT 06520, USA. dieter.soll@yale.edu.ORCID 0000-0002-3077-8986
Koji TamuraDepartment of Biological Science and Technology, Tokyo University of Science, Tokyo 125-8585, Japan. koji@rs.tus.ac.jp.
Tokyo University of Science · JPRIKEN Center for Sustainable Resource Science · JPYale University · US

Funding

TRANSFER RNAR01GM022854 · NIGMS · YALE UNIVERSITY · PI SOLL, DIETER · 1985 to 2016
$21.3M
Japan Society for the Promotion of Science 15K18469NIGMS NIH HHS R01 GM022854
6 · The paper itself

Abstract

Protein lysine acetylation is a widely conserved posttranslational modification in all three domains of life. Lysine acetylation frequently occurs in aminoacyl-tRNA synthetases (aaRSs) from many organisms. In this study, we determined the impact of the naturally occurring acetylation at lysine-73 (K73) in

Indexed as

alanyl-tRNA synthetaseclass II aminoacyl-tRNA synthetaseexpanded genetic codelysine acetylationposttranslational modification

Identifiers

PMID30274179
PMCPMC6209979
OpenAlexW2894001013

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.