Trial reportPsychiatry research2018
History of childhood emotional abuse predicts lower resting-state high-frequency heart rate variability in depressed women.
Trial report in Psychiatry research, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
18 citing papers in PubMed.
- Objective prenatal sleep and adverse childhood experiences in a proof-of-concept observational mixed methods study.iScience · 2026Article
- Perceived sleep disturbance in healthy women with a history of childhood emotional abuse is not reflected in objective sleep measures or nocturnal heart rate variability.Frontiers in psychiatry · 2026Article
- Exploration of wearable sensor measures associated with panic attacks differs across mental health conditions.Frontiers in digital health · 2026Article
- Adverse childhood experiences, age at menopause, and vasomotor symptoms among mid-life Latine adults in California.Evolutionary human sciences · 2026Article
- Long-term alteration of heart rate variability following childhood maltreatment: Results of a general population study.European psychiatry : the journal of the Association of European Psychiatrists · 2025Article
- Dampening of positive affect partially accounts for the association between women's history of child maltreatment and current depressive symptoms.BMC psychology · 2025Article
- Transdiagnostic indicators predict developmental changes in cognitive control resting-state networks.Development and psychopathology · 2023Article
- A Network Analysis Approach to Understanding the Relationship Between Childhood Trauma and Wellbeing Later in Life.Child psychiatry and human development · 2023Article
- The Immigrant Experience and Alcohol Use: Heart Rate as a Source of Risk and Resilience.Prevention science : the official journal of the Society for Prevention Research · 2023Article
- Digital Phenotyping for Differential Diagnosis of Major Depressive Episode: Narrative Review.JMIR mental health · 2023Review
- Early life stress and autonomic response to acute mental stress in individuals with coronary heart disease.Journal of traumatic stress · 2022Article
- A Web-Based Cognitive Behavioral Therapy, Mindfulness Meditation, and Yoga Intervention for Posttraumatic Stress Disorder: Single-Arm Experimental Clinical Trial.JMIR mental health · 2022Article
- Psychological Traumas and Cardiovascular Disease: A Case-Control Study.Healthcare (Basel, Switzerland) · 2021Article
- Emotion context insensitivity in depression: Toward an integrated and contextualized approach.Psychophysiology · 2021Review
- Yohimbine-Induced Reactivity of Heart Rate Variability in Unmedicated Depressed Patients With and Without Adverse Childhood Experience.Frontiers in psychiatry · 2021Article
- Cross system autonomic balance and regulation: Associations with depression and anxiety symptoms.Psychophysiology · 2020Article
- The relationship of trauma exposure to heart rate variability during wake and sleep in midlife women.Psychophysiology · 2020Article
- Associations Between Child Maltreatment, Autonomic Regulation, and Adverse Cardiovascular Outcome in an Urban Population: The HELIUS Study.Frontiers in psychiatry · 2020Article
Corrections and comments
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Authors and funding
4 authors.
Funding
Abstract
Childhood emotional abuse impairs emotion regulation and increases risk for major depressive disorder in adulthood. Mounting evidence suggests that decreased resting-state high-frequency heart rate variability, an index of parasympathetic function, represents a transdiagnostic biomarker of emotion dysregulation. We propose that adults with histories of major depressive disorder and childhood emotional abuse represent a subpopulation at particularly high risk to exhibit deficits in parasympathetic control. The current report compared resting-state high-frequency heart rate variability across three groups: (1) depressed women who endorsed childhood emotional abuse (N = 11); (2) depressed women without childhood emotional abuse (N = 19), and (3) never-depressed women without childhood emotional abuse (N = 22). Participants completed childhood trauma self-reports and assessment of resting-state high-frequency heart rate variability. ANCOVAs comparing the three groups after controlling for health-related, psychiatric, and respiratory factors were significant. Depressed women with childhood emotional abuse exhibited lower high-frequency heart rate variability than both groups without childhood emotional abuse (d's ranging from 0.81-0.92). Surprisingly, psychiatric factors were non-significant predictors, indicating that childhood emotional abuse may have a unique impact on autonomic functioning. Future research on larger samples is needed to disentangle the relative and synergistic burdens of depression and childhood trauma on physiologic indicators of emotion dysregulation.
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