ArticlePsychiatry research. Neuroimaging2018
Alexithymia and reactive aggression: The role of the amygdala.
Article in Psychiatry research. Neuroimaging, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
18 citing papers in PubMed.
- Effect of Childhood Trauma on Emotional Distress: A Chain-Mediated Effects of Alexithymia and Psychological Flexibility.Brain and behavior · 2025Article
- Relationship Between Alexithymia, Cognitive Function and the Pain and Emotional Symptoms in Adolescent Migraine Patients.Psychiatry investigation · 2025Article
- The relationship between core self-evaluation and cognitive failure in Chinese adolescents: the sequential mediating role of alexithymia and depression.BMC psychology · 2025Article
- The mediating effect of alexithymia in the symptom burden and depression in patients with maintenance hemodialysis.Frontiers in psychology · 2025Article
- Hippocampal subfield and amygdala volumes are associated with difficulties in emotion regulation of depressed patients with a history of childhood maltreatment.Frontiers in psychiatry · 2025Article
- Amygdala self-neuromodulation capacity as a window for process-related network recruitment.Philosophical transactions of the Royal Society of London. Series B, Biological sciences · 2024Article
- Relationships between Grey Matter Volume in the Bilateral Superior Frontal Gyrus and Reactive Aggression Varied by Level of Traditional Masculinity.Brain sciences · 2024Article
- Childhood maltreatment and aggressive behavior among college students: a serial mediation model of authenticity and alexithymia.Frontiers in psychiatry · 2024Article
- How does it feel? An exploration of neurobiological and clinical correlates of alexithymia in trauma-exposed police-officers with and without PTSD.European journal of psychotraumatology · 2023Article
- Characteristics and correlation of gray matter volume and somatic symptoms in adolescent patients with depressive disorder.Frontiers in psychiatry · 2023Article
- The Association of White Matter Tracts with Alexithymia among Individuals with Major Depressive Disorder.Experimental neurobiology · 2022Article
- Aggression, Alexithymia and Sense of Coherence in a Sample of Schizophrenic Outpatients.Healthcare (Basel, Switzerland) · 2022Article
- Adolescents' Attachment to Parents and Reactive-Proactive Aggression: The Mediating Role of Alexithymia.International journal of environmental research and public health · 2021Article
- Association between schizoid tendencies and aggressive behaviors: mediating and moderating influences in childhood trauma and life events among Chinese adolescents.Annals of general psychiatry · 2021Article
- Cold-Blooded and on Purpose: A Review of the Biology of Proactive Aggression.Brain sciences · 2021Review
- Understanding Emotions: Origins and Roles of the Amygdala.Biomolecules · 2021Review
- Understanding Brain Mechanisms of Reactive Aggression.Current psychiatry reports · 2020Review
- The role of monoamine oxidase A in the neurobiology of aggressive, antisocial, and violent behavior: A tale of mice and men.Progress in neurobiology · 2020Review
Corrections and comments
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Authors and funding
5 authors.
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Abstract
Past research suggests an association between reactive aggression and alexithymia, but neural mechanisms underlying this association remain unknown. Furthermore, the relationship between proactive aggression and alexithymia remains untested. This study aimed to: (1) test whether alexithymia is more related to reactive than proactive aggression; and (2) determine whether amygdala, insula, and/or anterior cingulate cortical (ACC) volume could be neurobiological mechanisms for this association. One hundred and fifty-six community males completed the Reactive-Proactive Aggression Questionnaire and the Toronto Alexithymia Scale. Amygdala, insula, and ACC volumes were assessed using MRI. Alexithymia was positively associated with reactive but not proactive aggression. Alexithymia was positively and bilaterally associated with amygdala and anterior cingulate volumes. Reactive aggression was positively associated with right amygdala volume. Controlling for right amygdala volume rendered the alexithymia-reactive aggression relationship non-significant. Results suggest that increased right amygdala volume is a common neurobiological denominator for both alexithymia and reactive aggression. Findings suggest that greater right hemisphere activation may reflect a vulnerability to negative affect, which in turn predisposes to experiencing negative emotions leading to increased aggression. Findings are among the first to explicate the nature of the alexithymia-aggression relationship, with potential clinical implications.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.