Evidence map›Paper›PMID 30273518›Full record

ArticlePlant signaling & behavior2018

Mitogen-activated protein kinase kinase 6 negatively regulates anthocyanin induction in Arabidopsis.

Rowan van Wersch, Fang Gao, Yuelin Zhang

Open access · bronzeAbstract read
In one paragraph

Article in Plant signaling & behavior, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
0.5field-weighted citation impact, top 36% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 15 citations in OpenAlex.

  1. Review
  2. Article
  3. Review
  4. Review
  5. MYB-Mediated Regulation of Anthocyanin Biosynthesis.International journal of molecular sciences · 2021
    Review
  6. Review
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Rowan van Werscha Department of Botany , University of British Columbia , Vancouver , BC , Canada.
Fang Gaoa Department of Botany , University of British Columbia , Vancouver , BC , Canada.
Yuelin Zhanga Department of Botany , University of British Columbia , Vancouver , BC , Canada.
University of British Columbia · CA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Arabidopsis mitogen-activated protein (MAP) kinase kinase 6 (MKK6) has previously been shown to play important roles in plant immunity and cytokinesis. Here we report that it is also involved in the negative regulation of anthocyanin biosynthesis in Arabidopsis. Elevated anthocyanin levels are observed in mkk6 knock out mutant plants. RNA-sequencing analysis revealed that the expression level of MYB75 (Myb transcription factor 75), which encodes a key positive regulator of anthocyanin biosynthesis, is up-regulated in mkk6 mutant plants, suggesting that increased MYB75 expression contributes to the elevated anthocyanin levels. In addition, suppression of high sucrose-induced anthocyanin production by pathogen associated molecular pattern-triggered immunity is also dependent on MKK6, further supporting that MKK6 is a key negative regulator of anthocyanin biosynthesis in Arabidopsis.

Indexed as

AnthocyaninsArabidopsisArabidopsis ProteinsGene Expression Regulation, PlantMAP Kinase Kinase 6Transcription FactorsAnthocyaninsArabidopsis ProteinsAT1G56650 protein, ArabidopsisMAP Kinase Kinase 6Transcription FactorsanthocyaninArabidopsisMAP kinase cascadeMKK6MYB75

Identifiers

PMID30273518
PMCPMC6204826
OpenAlexW2894657247

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.