Evidence map›Paper›PMID 30272668›Full record

ArticleJournal of visualized experiments : JoVE2018

Mouse Body Temperature Measurement Using Infrared Thermometer During Passive Systemic Anaphylaxis and Food Allergy Evaluation.

Yu Kawakami, Rachel Sielski, Toshiaki Kawakami

Open access · bronzeAbstract readVideo-Audio Media
In one paragraph

Article in Journal of visualized experiments : JoVE, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed
1.4field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 43 citations in OpenAlex.

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  9. Effects of acute ΔBrain research · 2024
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  18. Increased Expression ofIn vivo (Athens, Greece)
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Yu KawakamiDivision of Cell Biology, La Jolla Institute for Allergy and Immunology.
Rachel SielskiDivision of Cell Biology, La Jolla Institute for Allergy and Immunology.
Toshiaki KawakamiDivision of Cell Biology, La Jolla Institute for Allergy and Immunology; toshi@lji.org.
La Jolla Institute for Immunology · US

Funding

Mast cell Stat5-regulatory pathway in atopic dermatitisR01AR064418 · NIAMS · LA JOLLA INSTITUTE FOR IMMUNOLOGY · PI KAWAKAMI, TOSHIAKI · 2014 to 2018
$1.9M
Interaction of histamine-releasing factor with immunoglobulins in asthmaR01HL124283 · NHLBI · LA JOLLA INSTITUTE FOR IMMUNOLOGY · PI KAWAKAMI, TOSHIAKI · 2014 to 2017
$1.9M
Anaphylaxis and IgE heterogeneityR21AI115534 · NIAID · LA JOLLA INSTITUTE FOR IMMUNOLOGY · PI KAWAKAMI, TOSHIAKI · 2015 to 2016
$484k
Blockade of histamine-releasing factor as a new prophylactic and therapeutic strategy for food allergyR41AI124734 · NIAID · ABWIZ BIO, INC. · PI KAWAKAMI, TOSHIAKI, MARUYAMA, TOSHIAKI · 2016 to 2016
$230k
NHLBI NIH HHS R01 HL124283NIAID NIH HHS R21 AI115534NIAID NIH HHS R41 AI124734NIAMS NIH HHS R01 AR064418
6 · The paper itself

Abstract

Mouse body temperature measurement is of paramount importance for investigating allergies and anaphylactic symptoms. Rectal probes for temperature readings is common, and they have been proven to be accurate and invaluable in this regard. However, this method of temperature measurement requires the mice to be anesthetized in order to insert the probe without injury to the animal. This limits the ability to observe other phenotypes of the mouse simultaneously. In order to investigate other phenotypes while measuring temperatures, rectal probes are not ideal, and another method is desired. Here, we introduce a noninvasive method of temperature measurement that foregoes the requirement for mouse anesthesia while maintaining equal reliability to rectal probes in measuring body temperature. We use an infrared thermometer that detects body surface temperatures at ranges between 2 and 150 mm. This method of body temperature measurement is successful in reliably replicating temperature change trends during passive system anaphylaxis experiments in mice. We show that body surface temperatures are about 2.0 °C lower than rectal probe measurements, but the degree of temperature drop follows the same trend. Furthermore, we use the same technique to observe mice in a food allergy model to evaluate temperature and activity levels simultaneously.

Indexed as

AnaphylaxisAnimalsFemaleFood HypersensitivityHumansInfrared RaysMiceTemperatureThermometers

Identifiers

PMID30272668
PMCPMC6235190
OpenAlexW2890449262

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.