Evidence map›Paper›PMID 30272171›Full record

GuidelineThe Journal of clinical endocrinology and metabolism2018

Congenital Adrenal Hyperplasia Due to Steroid 21-Hydroxylase Deficiency: An Endocrine Society Clinical Practice Guideline.

Phyllis W Speiser, Wiebke Arlt, Richard J Auchus, Laurence S Baskin, Gerard S Conway, Deborah P Merke, Heino F L Meyer-Bahlburg, Walter L Miller, M Hassan Murad, Sharon E Oberfield and 1 more

Erratum issuedAbstract readPractice Guideline
In one paragraph

Guideline in The Journal of clinical endocrinology and metabolism, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 521 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
521citing papers in PubMed, 3 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

521 citing papers in PubMed, 3 syntheses or guidelines pooled it.

  1. Guideline
  2. Pooled it
  3. Pooled it
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  12. Observational
  13. Review
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  18. Article
  19. Approach to the patient: investigation of postmenopausal androgen excess.The Journal of clinical endocrinology and metabolism · 2026
    Review
  20. Article

461 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

11 authors.

Phyllis W SpeiserCohen Children's Medical Center of New York, New York, New York.
Wiebke ArltUniversity of Birmingham, Birmingham, United Kingdom.
Richard J AuchusUniversity of Michigan, Ann Arbor, Michigan.
Laurence S BaskinUniversity of California San Francisco, San Francisco, California.
Gerard S ConwayUniversity College London Hospitals, London, United Kingdom.
Deborah P MerkeNational Institutes of Health Clinical Center, Bethesda, Maryland.
Heino F L Meyer-BahlburgNew York State Psychiatric Institute, Vagelos College of Physicians & Surgeons of Columbia University, New York, New York.
Walter L MillerUniversity of California San Francisco, San Francisco, California.
M Hassan MuradMayo Clinic's Evidence-Based Practice Center, Rochester, Minnesota.
Sharon E OberfieldNewYork-Presbyterian, Columbia University Medical Center, New York, New York.
Perrin C WhiteUniversity of Texas Southwestern Medical Center, Dallas, Texas.

Funding

Natural History Study of Patients with Excess AndrogenZIAHD008934 · NICHD · EUNICE KENNEDY SHRIVER NATIONAL INSTITUTE OF CHILD HEALTH & HUMAN DEVELOPMENT · PI MERKE, DEBORAH · 2013 to 2021
$238k
Medical Research Council G0900567
6 · The paper itself

Abstract

Objective: To update the congenital adrenal hyperplasia due to steroid 21-hydroxylase deficiency clinical practice guideline published by the Endocrine Society in 2010. Conclusions: The writing committee presents updated best practice guidelines for the clinical management of congenital adrenal hyperplasia based on published evidence and expert opinion with added considerations for patient safety, quality of life, cost, and utilization.

Indexed as

Adrenal Hyperplasia, CongenitalCost-Benefit AnalysisEndocrinologyFemaleFetal TherapiesGenetic CounselingGlucocorticoidsHumansInfant, NewbornLong-Term CareNeonatal ScreeningPatient SafetyQuality of LifeSocieties, MedicalTherapies, InvestigationalGlucocorticoids

Identifiers

PMID30272171
PMCPMC6456929

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.