ArticleCerebral cortex (New York, N.Y. : 1991)2019
Early-Emerging Sulcal Patterns Are Atypical in Fetuses with Congenital Heart Disease.
Article in Cerebral cortex (New York, N.Y. : 1991), 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 51 papers, 2 of them syntheses that pooled it.
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Who cites it
51 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- Neurosonographic Evaluation of Cerebral Cortical Development in Fetuses With Congenital Heart Disease: A Systematic Review of the Literature.Prenatal diagnosis · 2025Pooled it
- Meta-regression of sulcal patterns, clinical and environmental factors on neurodevelopmental outcomes in participants with multiple CHD types.Cerebral cortex (New York, N.Y. : 1991) · 2024Pooled it
- Intraoperative sodium range affects white matter microstructure in neonatal congenital heart disease.International journal of cardiology. Congenital heart disease · 2026Article
- Genetic insights on the mechanisms of human cortical folding.bioRxiv : the preprint server for biology · 2026Article
- Evaluating reliability of automated quantitative brain morphometry from fetal T2-weighted MRI.Frontiers in neuroscience · 2026Article
- Cortical morphology and cognitive impairments in adolescents with complex congenital heart disease.Brain communications · 2026Article
- Placental and Fetal Brain Volumes in Congenital Heart Disease Are Smallest Among Fetuses With Genetic Abnormalities.Prenatal diagnosis · 2025Article
- Mechanics of the Spatiotemporal Evolution of Sulcal Pits in the Folding Brain.Human brain mapping · 2025Article
- Cord blood levels of insulin-like growth factor-1 and insulin-like growth factor binding protein-3 correlate with perinatal brain development in fetal congenital heart disease.Ultrasound in obstetrics & gynecology : the official journal of the International Society of Ultrasound in Obstetrics and Gynecology · 2025Observational
- Longitudinal magnetic resonance imaging reveals differences in cortical expansion in fetuses with congenital heart defects.Cerebral cortex (New York, N.Y. : 1991) · 2025Article
- Graph-based prototype inverse-projection for identifying cortical sulcal pattern abnormalities in congenital heart disease.Medical image analysis · 2025Article
- Foetal cortical expansion is associated with neurodevelopmental outcome at 2-years in congenital heart disease: a longitudinal follow-up study.EBioMedicine · 2025Article
- Impact of high maternal body mass index on fetal cerebral cortical and cerebellar volumes.Journal of perinatal medicine · 2025Article
- T2*-Relaxometry MRI to Assess Third Trimester Placental and Fetal Brain Oxygenation and Placental Characteristics in Healthy Fetuses and Fetuses With Congenital Heart Disease.Journal of magnetic resonance imaging : JMRI · 2025Article
- Alteration in Cortical Structure Mediating the Impact of Blood Oxygen-Carrying Capacity on Gross Motor Skills in Infants With Complex Congenital Heart Disease.Human brain mapping · 2025Article
- Contrasting neonatal brain morphometry and its impact on neurodevelopmental outcome between preterm birth and congenital heart disease.Imaging neuroscience (Cambridge, Mass.) · 2025Article
- Quantifying the Timing of Gyral and Sulcal Formation Relative to Growth in the Ferret Cerebral Cortex.Developmental neuroscience · 2025Article
- Structural Covariance Networks in the Fetal Brain Reveal Altered Neurodevelopment for Specific Subtypes of Congenital Heart Disease.Journal of the American Heart Association · 2024Article
- Placental-Heart Axis: An Evolutionary Perspective.International journal of molecular sciences · 2024Review
- Total and Regional Brain Volumes in Fetuses With Congenital Heart Disease.Journal of magnetic resonance imaging : JMRI · 2024Article
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Authors and funding
14 authors.
Funding
Abstract
Fetuses with congenital heart disease (CHD) have third trimester alterations in cortical development on brain magnetic resonance imaging (MRI). However, the intersulcal relationships contributing to global sulcal pattern remain unknown. This study applied a novel method for examining the geometric and topological relationships between sulci to fetal brain MRIs from 21-30 gestational weeks in CHD fetuses (n = 19) and typically developing (TD) fetuses (n = 17). Sulcal pattern similarity index (SI) to template fetal brain MRIs was determined for the position, area, and depth for corresponding sulcal basins and intersulcal relationships for each subject. CHD fetuses demonstrated altered global sulcal patterns in the left hemisphere compared with TD fetuses (TD [SI, mean ± SD]: 0.822 ± 0.023, CHD: 0.795 ± 0.030, P = 0.002). These differences were present in the earliest emerging sulci and were driven by differences in the position of corresponding sulcal basins (TD: 0.897 ± 0.024, CHD: 0.878 ± 0.019, P = 0.006) and intersulcal relationships (TD: 0.876 ± 0.031, CHD: 0.857 ± 0.018, P = 0.033). No differences in cortical gyrification index, mean curvature, or surface area were present. These data suggest our methods may be more sensitive than traditional measures for evaluating cortical developmental alterations early in gestation.
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