ArticleCerebral cortex (New York, N.Y. : 1991)2019
Hippocampal Shape Maturation in Childhood and Adolescence.
Article in Cerebral cortex (New York, N.Y. : 1991), 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 28 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
28 citing papers in PubMed, 49 citations in OpenAlex.
- The Amygdala and Politics.Brain sciences · 2026Review
- Surface expansion regionalization of the hippocampus in early brain development.Developmental cognitive neuroscience · 2026Article
- Accelerated Magnetic Seizure Therapy for Non-Suicidal Self-Injury in Adolescents With Bipolar Depression.CNS neuroscience & therapeutics · 2026Article
- Safety-relevant experience reshapes neural codes for ambiguous threat in adolescents.Social cognitive and affective neuroscience · 2026Article
- The promise of infant MRI in psychiatry: toward a framework for neural network measures in early emotional and behavioral risk identification and new intervention targets.Molecular psychiatry · 2026Review
- Does restrictive anorexia nervosa impact brain aging? A machine learning approach to estimate age based on brain structure.Computers in biology and medicine · 2025Article
- Hormonal contraceptives in adolescence impact the neuroimmune environment of the medial prefrontal cortex and hippocampus in female rats.Brain, behavior, and immunity · 2025Article
- Verifying the concordance between motion corrected and conventional MPRAGE for pediatric morphometric analysis.Frontiers in neuroscience · 2025Article
- Antiamnesic and Neurotrophic Effects ofBehavioural neurology · 2025Article
- Modified neuroimmune processes and emotional behaviour in weaned and late adolescent male and female mice born via caesarean section.Scientific reports · 2024Article
- Reduced hippocampal volume unmasks distinct impacts of cumulative adverse childhood events (ACEs) on psychotic-like experiences in late childhood and early adolescence.Psychoneuroendocrinology · 2024Article
- Preterm Birth Alters the Regional Development and Structural Covariance of Cerebellum at Term-Equivalent Age.Cerebellum (London, England) · 2024Article
- A longitudinal study of the relationship between alcohol-related blackouts and attenuated structural brain development.Developmental cognitive neuroscience · 2024Article
- Longitudinal study on hippocampal subfields and glucose metabolism in early psychosis.Schizophrenia (Heidelberg, Germany) · 2024Article
- Early adversity causes sex-specific deficits in perforant pathway connectivity and contextual memory in adolescent mice.Biology of sex differences · 2024Article
- Gestational glyphosate exposure and early childhood neurodevelopment in a Puerto Rico birth cohort.Environmental research · 2024Article
- Longitudinal hippocampal subfield development associated with psychotic experiences in young people.Translational psychiatry · 2024Article
- Psychological Resilience Interventions for Adolescents during the COVID-19 Pandemic.Behavioral sciences (Basel, Switzerland) · 2023Article
- Hippocampal anterior- posterior shift in childhood and adolescence.Progress in neurobiology · 2023Article
- A fast and robust hippocampal subfields segmentation: HSF revealing lifespan volumetric dynamics.Frontiers in neuroinformatics · 2023Article
Corrections and comments
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Authors and funding
5 authors at 1 institution in 1 country.
Funding
Abstract
The hippocampus is a subcortical structure critical for learning and memory, and a thorough understanding of its neurodevelopment is important for studying these processes in health and disease. However, few studies have quantified the typical developmental trajectory of the structure in childhood and adolescence. This study examined the cross-sectional age-related changes and sex differences in hippocampal shape in a multisite, multistudy cohort of 1676 typically developing children (age 1-22 years) using a novel intrinsic brain mapping method based on Laplace-Beltrami embedding of surfaces. Significant age-related expansion was observed bilaterally and nonlinear growth was observed primarily in the right head and tail of the hippocampus. Sex differences were also observed bilaterally along the lateral and medial aspects of the surface, with females exhibiting relatively larger surface expansion than males. Additionally, the superior posterior lateral surface of the left hippocampus exhibited an age-sex interaction with females expanding faster than males. Shape analysis provides enhanced sensitivity to regional changes in hippocampal morphology over traditional volumetric approaches and allows for the localization of developmental effects. Our results further support evidence that hippocampal structures follow distinct maturational trajectories that may coincide with the development of learning and memory skills during critical periods of development.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.