ArticleCerebral cortex (New York, N.Y. : 1991)2018
Direct Relay Pathways from Lemniscal Auditory Thalamus to Secondary Auditory Field in Mice.
Article in Cerebral cortex (New York, N.Y. : 1991), 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 17 papers.
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Who cites it
17 citing papers in PubMed, 33 citations in OpenAlex.
- Orthogonal spectral and temporal envelope representation during the onset phase in auditory cortex.iScience · 2025Article
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- Noncanonical short-latency auditory pathway directly activates deep cortical layers.Nature communications · 2025Article
- Mouse auditory cortex sub-fields receive neuronal projections from MGB subdivisions independently.Scientific reports · 2024Article
- Whole-brain responses to visual and auditory stimuli in anesthetized and minimally restrained awake mice using quiet zero echo time fMRI.Imaging neuroscience (Cambridge, Mass.) · 2024Article
- Bilateral widefield calcium imaging reveals circuit asymmetries and lateralized functional activation of the mouse auditory cortex.Proceedings of the National Academy of Sciences of the United States of America · 2023Article
- Distinct nonlinear spectrotemporal integration in primary and secondary auditory cortices.Scientific reports · 2023Article
- Biological constraints on stereotaxic targeting of functionally-defined cortical areas.Cerebral cortex (New York, N.Y. : 1991) · 2023Article
- Distinct nonlinear spectrotemporal integration in primary and secondary auditory cortices.bioRxiv : the preprint server for biology · 2023Article
- Consider the pons: bridging the gap on sensory prediction abnormalities in schizophrenia.Trends in neurosciences · 2022Review
- Sparse Coding in Temporal Association Cortex Improves Complex Sound Discriminability.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2021Article
- Inhibitory gating of coincidence-dependent sensory binding in secondary auditory cortex.Nature communications · 2021Article
- Cellular and Widefield Imaging of Sound Frequency Organization in Primary and Higher Order Fields of the Mouse Auditory Cortex.Cerebral cortex (New York, N.Y. : 1991) · 2020Article
- Reciprocal connectivity between secondary auditory cortical field and amygdala in mice.Scientific reports · 2019Article
- Modulation of tonotopic ventral medial geniculate body is behaviorally relevant for speech recognition.eLife · 2019Article
- Article
- Article
Corrections and comments
- Erratum issued
Authors and funding
10 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Tonotopy is an essential functional organization in the mammalian auditory cortex, and its source in the primary auditory cortex (A1) is the incoming frequency-related topographical projections from the ventral division of the medial geniculate body (MGv). However, circuits that relay this functional organization to higher-order regions such as the secondary auditory field (A2) have yet to be identified. Here, we discovered a new pathway that projects directly from MGv to A2 in mice. Tonotopy was established in A2 even when primary fields including A1 were removed, which indicates that tonotopy in A2 can be established solely by thalamic input. Moreover, the structural nature of differing thalamocortical connections was consistent with the functional organization of the target regions in the auditory cortex. Retrograde tracing revealed that the region of MGv input to a local area in A2 was broader than the region of MGv input to A1. Consistent with this anatomy, two-photon calcium imaging revealed that neuronal responses in the thalamocortical recipient layer of A2 showed wider bandwidth and greater heterogeneity of the best frequency distribution than those of A1. The current study demonstrates a new thalamocortical pathway that relays frequency information to A2 on the basis of the MGv compartmentalization.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.