Evidence map›Paper›PMID 30272106›Full record

SynthesisThe journal of nutrition, health & aging2018

Systematic Review and Meta-Analysis of the Association between Sarcopenia and Dysphagia.

W-T Zhao, M Yang, H-M Wu, L Yang, X-M Zhang, Y Huang

Registry-linked trialOpen access · greenAbstract readMeta-AnalysisSystematic Review
PubMed Full text at PMC Publisher
In one paragraph

Synthesis in The journal of nutrition, health & aging, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05173051 (Medication Intake of Solid Dosage Forms), which is not on this map. Cited by 67 papers, 7 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
67citing papers in PubMed, 7 pooled it
20.3field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT05173051 nacompletednot on this mapstarted 2022, after this paper: background citation

Medication Intake of Solid Dosage Forms: A Risk Factor for Patients With Stroke-induced Dysphagia?

TypeinterventionalSponsorKarl Landsteiner University of Health SciencesRan2022 to 2023Enrolled60ConditionsCerebral Infarction, Stroke, Acute, Stroke, DysphagiaArmsSolid Medication intake vs. crushed medication intake
3 · Its place in the literature

Who cites it

67 citing papers in PubMed, 7 syntheses or guidelines pooled it, 115 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Pooled it
  4. Pooled it
  5. Pooled it
  6. Pooled it
  7. Pooled it
  8. Trial
  9. Review
  10. Article
  11. Article
  12. Observational
  13. Article
  14. Article
  15. Article
  16. Article
  17. Article
  18. Article
  19. A comparison of oral health, nutrition, and swallowing function in older adults with and without sarcopenia: A cross-sectional study.Nutrition in clinical practice : official publication of the American Society for Parenteral and Enteral Nutrition · 2025
    Article
  20. Article

7 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 1 country.

W-T ZhaoXue-mei Zhang, BS, is Professor,The Center of Gerontology and Geriatrics, West China Hospital, Sichuan University, National Clinical Research Center of Geriatrics, West China Hopital, Sichuan University, Chengdu, China. No.37 Guoxue Alley, Wuhou District, Chengdu City, Sichuan Province, PR China. E-mail address: zxm0709@126.com. Telephone number: 18980601339.
M Yang
H-M Wu
L Yang
X-M Zhang
Y Huang
Sichuan University · CNWuhou District People's Hospital, Chengdu · CNThe Sixth People's Hospital of Shenyang · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesSarcopenia, an age-related decrease in muscle mass and function, is associated with several potential adverse health outcomes. Its association with another age-related syndrome, dysphagia remains unclear. This systematic review and meta-analysis aims to explore the association between sarcopenia and dysphagia.

methodsPubMed, Embase, Scopus and CINAHL were searched for cross-sectional, case-control and cohort studies that investigated the association between sarcopenia and dysphagia. First author, publication year, study type, sample size, inclusion and exclusion criteria, participant demographics, definition and measurement for evaluation of sarcopenia and dysphagia, main outcomes were retrieved. The association between sarcopenia and dysphagia were expressed by odds ratio (OR) and 95% confidence interval (CI).

results9 studies are eligible in the systematic review, and 5 cross-sectional studies comprising 913 participants which showed dichotomous classification of sarcopenia and dysphagia were included in the meta-analysis. The crude odds ratios (ORs) were extracted from 5 studies, and 4 of them also provide adjusted ORs. The crude ORs between sarcopenia and dysphagia is 6.17 (95% CI, 3.81- 10.00), after adjusting for some confounders, such as age, sex, Barthel Index score, nutritional status, sarcopenia is also have an association with dysphagia (adjusted ORs, 4.06; 95% CI, 2.27-7.29). The subgroup analysis showed that there was no significant difference between different sarcopenia diagnostic criteria, assessment tools of skeletal muscle mass and dysphagia.

conclusionSarcopenia was positively associated with dysphagia. Prevention and screening of dysphagia is essential among sarcopenic old patients. The causal relationship requires more prospective cohort study for confirmation.

Indexed as

AgedAged, 80 and overCase-Control StudiesCross-Sectional StudiesDeglutition DisordersFemaleHumansMaleMuscle, SkeletalNutritional StatusOdds RatioProspective StudiesSarcopeniaagingdysphagiaorder peopleSarcopenia

Identifiers

PMID30272106
PMCPMC12876361
OpenAlexW2807288894

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.