Evidence map›Paper›PMID 30272041›Full record

ArticleCurrent opinion in biomedical engineering2017

Magnetic resonance molecular imaging for non-invasive precision cancer diagnosis.

Zheng-Rong Lu

Abstract read
In one paragraph

Article in Current opinion in biomedical engineering, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Review
  2. Review
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

1 author.

Zheng-Rong LuCase Center for Biomolecular Engineering, Department of Biomedical Engineering, Case Western Reserve University, 10900 Euclid Avenue, Cleveland, Ohio 44106, USA.

Funding

Image-guided EMT inhibition for treating metastatic breast cancerR01CA194518 · NCI · CASE WESTERN RESERVE UNIVERSITY · PI LU, ZHENG-RONG, SCHIEMANN, WILLIAM · 2015 to 2019
$2.4M
Targeted MRI contrast agents for differential diagnosis of prostate cancerR01CA211762 · NCI · CASE WESTERN RESERVE UNIVERSITY · PI LU, ZHENG-RONG · 2017 to 2021
$2.1M
NCI NIH HHS R01 CA194518NCI NIH HHS R01 CA211762
6 · The paper itself

Abstract

Magnetic resonance imaging (MRI) is a non-invasive clinical imaging modality for high-resolution imaging of soft tissues. Magnetic resonance molecular imaging (MRMI) has the potential to provide high-resolution delineation of cancer for precision medicine. However, its clinical application is hampered by the low sensitivity of contrast enhanced MRI and the lack of safe and effective targeted MRI contrast agents. Significant progress has recently been made in the design and development of novel clinically translatable targeted MRI contrast agents for MRMI of cancer. The challenges and strategies for designing the safe and effective targeted MRI contrast agents are discussed here. Some of the recent progresses in MRMI are also highlighted. These progresses provide a new paradiagm for the design and development of safe and effective MRI contrast agents for clinical translation and pave the pave for clinical application of MRMI in precision management of cancer.

Identifiers

PMID30272041
PMCPMC6158012

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.