ArticleCommunications biology2018
Sea turtle fibropapilloma tumors share genomic drivers and therapeutic vulnerabilities with human cancers.
Article in Communications biology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
20 citing papers in PubMed.
- The Paipu framework enables creation of a large-scale mammalian cancer transcriptomics atlas.bioRxiv : the preprint server for biology · 2026Article
- Fibropapillomatosis: A Review of the Disease with Attention to the Situation Northern Coast of Brazil.Animals : an open access journal from MDPI · 2024Review
- International overview of sea turtle fibropapillomatosis: a survey of expert opinions and trends.Frontiers in cell and developmental biology · 2024Article
- Immunity in Sea Turtles: Review of a Host-Pathogen Arms Race Millions of Years in the Running.Animals : an open access journal from MDPI · 2023Review
- A subpopulation of green turtle suprabasal epidermal cells are Langerin+ and migrate under in vitro stimulation of the chemokine CCL21.Veterinary research communications · 2022Article
- Preparation of recombinant glycoprotein B (gB) of Chelonid herpesvirus 5 (ChHV5) for antibody production and its application for infection detection in sea turtles.Scientific reports · 2022Article
- Occurrence of Fibropapillomatosis in Green Turtles (Animals : an open access journal from MDPI · 2022Article
- Influence of Sunlight on Vitamin D and Health Status in Green (Animals : an open access journal from MDPI · 2022Article
- Adaptive evolution of major histocompatibility complex class I immune genes and disease associations in coastal juvenile sea turtles.Royal Society open science · 2022Article
- Sea Turtles in the Cancer Risk Landscape: A Global Meta-Analysis of Fibropapillomatosis Prevalence and Associated Risk Factors.Pathogens (Basel, Switzerland) · 2021Article
- Evolutionary Comparisons of Chelonid Alphaherpesvirus 5 (ChHV5) Genomes from Fibropapillomatosis-Afflicted Green (Animals : an open access journal from MDPI · 2021Article
- Environmental DNA monitoring of oncogenic viral shedding and genomic profiling of sea turtle fibropapillomatosis reveals unusual viral dynamics.Communications biology · 2021Article
- Insights on Immune Function in Free-Ranging Green Sea Turtles (Animals : an open access journal from MDPI · 2021Article
- The Concurrent Detection of Chelonid Alphaherpesvirus 5 andAnimals : an open access journal from MDPI · 2021Article
- Molecular characterization of a marine turtle tumor epizootic, profiling external, internal and postsurgical regrowth tumors.Communications biology · 2021Article
- Genotype data not consistent with clonal transmission of sea turtle fibropapillomatosis or goldfish schwannoma.Wellcome open research · 2021Article
- Transcriptomic Profiling of Fibropapillomatosis in Green Sea Turtles (Frontiers in immunology · 2021Article
- Article
- When is a lab animal not a lab animal?Lab animal · 2020Article
- Perspectives on the expansion of human precision oncology and genomic approaches to sea turtle fibropapillomatosis.Communications biology · 2019Article
Corrections and comments
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Authors and funding
13 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Wildlife populations are under intense anthropogenic pressures, with the geographic range of many species shrinking, dramatic reductions in population numbers and undisturbed habitats, and biodiversity loss. It is postulated that we are in the midst of a sixth (Anthropocene) mass extinction event, the first to be induced by human activity. Further, threatening vulnerable species is the increased rate of emerging diseases, another consequence of anthropogenic activities. Innovative approaches are required to help maintain healthy populations until the chronic underlying causes of these issues can be addressed. Fibropapillomatosis in sea turtles is one such wildlife disease. Here, we applied precision-medicine-based approaches to profile fibropapillomatosis tumors to better understand their biology, identify novel therapeutics, and gain insights into viral and environmental triggers for fibropapillomatosis. We show that fibropapillomatosis tumors share genetic vulnerabilities with human cancer types, revealing that they are amenable to treatment with human anti-cancer therapeutics.
Identifiers
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.