Evidence map›Paper›PMID 30271933›Full record

ArticleCommunications biology2018

Multiple claudin-claudin

Jun Zhao, Evan S Krystofiak, Angela Ballesteros, Runjia Cui, Christina M Van Itallie, James M Anderson, Cristina Fenollar-Ferrer, Bechara Kachar

Open access · goldAbstract read
In one paragraph

Article in Communications biology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 50 papers.

0numbers the graph read from it
0cells of the map it votes in
50citing papers in PubMed
2.9field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

50 citing papers in PubMed, 78 citations in OpenAlex.

  1. Review
  2. Review
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Charcot-Marie-Tooth disease type 1E: Clinical Natural History and Molecular Impact ofmedRxiv : the preprint server for health sciences · 2025
    Article
  10. Ion and water permeation through claudin-10b and claudin-15 paracellular channels.Computational and structural biotechnology journal · 2024
    Article
  11. Article
  12. Article
  13. Article
  14. Review
  15. Review
  16. Article
  17. Review
  18. Review
  19. Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 4 institutions in 1 country.

Jun ZhaoLaboratory of Cell Structure and Dynamics, National Institute on Deafness and Other Communication Disorders, 35A Convent Drive, Bethesda, MD, 20892, USA.
Evan S KrystofiakLaboratory of Cell Structure and Dynamics, National Institute on Deafness and Other Communication Disorders, 35A Convent Drive, Bethesda, MD, 20892, USA.
Angela BallesterosLaboratory of Cell Structure and Dynamics, National Institute on Deafness and Other Communication Disorders, 35A Convent Drive, Bethesda, MD, 20892, USA.
Runjia CuiLaboratory of Cell Structure and Dynamics, National Institute on Deafness and Other Communication Disorders, 35A Convent Drive, Bethesda, MD, 20892, USA.
Christina M Van ItallieLaboratory of Tight Junction Structure and Function, National Heart, Lung, and Blood Institute, 50 South Drive, Bethesda, MD, 20892, USA.
James M AndersonLaboratory of Tight Junction Structure and Function, National Heart, Lung, and Blood Institute, 50 South Drive, Bethesda, MD, 20892, USA.
Cristina Fenollar-FerrerComputational Structural Biology Unit, National Institute of Neurological Disorders and Stroke, 35 Convent Drive, Bethesda, MD, 20892, USA. cristina.fenollarferrer@nih.gov.
Bechara KacharLaboratory of Cell Structure and Dynamics, National Institute on Deafness and Other Communication Disorders, 35A Convent Drive, Bethesda, MD, 20892, USA. kacharb@nidcd.nih.gov.
National Institute on Deafness and Other Communication Disorders · USNational Heart Lung and Blood Institute · USNational Cancer Institute · USNational Institute of Neurological Disorders and Stroke · US

Funding

Advanced Imaging CoreZICDC000081 · NIDCD · NATIONAL INSTITUTE ON DEAFNESS AND OTHER COMMUNICATION DISORDERS · PI WINKLER, DENNIS · 2012 to 2025
$17.4M
Molecular organization of intercellular junctions in the inner earZIADC000009 · NIDCD · NATIONAL INSTITUTE ON DEAFNESS AND OTHER COMMUNICATION DISORDERS · PI KACHAR, BECHARA · 2012 to 2020
$5.5M
MOLECULAR BASIS OF TRANSDUCTION IN AUDITORY SENSORY ORGANSZ01DC000002 · NIDCD · NATIONAL INSTITUTE ON DEAFNESS AND OTHER COMMUNICATION DISORDERS · PI KACHAR, BECHARA · 1989 to 2008
$3.9M
Intramural NIH HHS Z01 DC000002Intramural NIH HHS ZIC DC000081
6 · The paper itself

Abstract

Tight junctions consist of a network of sealing strands that create selective ion permeability barriers between adjoining epithelial or endothelial cells. The current model for tight junction strands consists of paired rows of claudins (Cldn) coupled by a

Identifiers

PMID30271933
PMCPMC6123731
OpenAlexW2804470197

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.