Evidence map›Paper›PMID 30271928›Full record

ArticleCommunications biology2018

Erythrocytes lacking the Langereis blood group protein ABCB6 are resistant to the malaria parasite

Elizabeth S Egan, Michael P Weekes, Usheer Kanjee, Jale Manzo, Ashwin Srinivasan, Christine Lomas-Francis, Connie Westhoff, Junko Takahashi, Mitsunobu Tanaka, Seishi Watanabe and 4 more

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Communications biology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
2.3field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 23 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Article
  5. Article
  6. Sickle Cell Trait Modulates the Proteome and Phosphoproteome ofFrontiers in cellular and infection microbiology · 2021
    Article
  7. Article
  8. Review
  9. Article
  10. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 6 institutions in 3 countries.

Elizabeth S EganDepartment of Immunology and Infectious Diseases, Harvard T.H. Chan School of Public Health, Boston, 02115, MA, USA. eegan@stanford.edu.
Michael P WeekesDepartment of Cell Biology, Harvard Medical School, Boston, 02115, MA, USA.ORCID http://orcid.org/0000-0003-3196-5545
Usheer KanjeeDepartment of Immunology and Infectious Diseases, Harvard T.H. Chan School of Public Health, Boston, 02115, MA, USA.
Jale ManzoDepartment of Immunology and Infectious Diseases, Harvard T.H. Chan School of Public Health, Boston, 02115, MA, USA.
Ashwin SrinivasanDepartment of Pediatrics, Stanford University School of Medicine, Stanford, 93205, CA, USA.
Christine Lomas-FrancisThe Laboratory of Immunohematology and Genomics, New York Blood Center, New York, 10065, NY, USA.
Connie WesthoffThe Laboratory of Immunohematology and Genomics, New York Blood Center, New York, 10065, NY, USA.
Junko TakahashiJapanese Red Cross Kinki Block Blood Center, Osaka, Japan.
Mitsunobu TanakaJapanese Red Cross Kinki Block Blood Center, Osaka, Japan.
Seishi WatanabeJapanese Red Cross Kyushu Block Blood Center, Fukuoka, Japan.
Carlo BrugnaraDepartment of Laboratory Medicine, Boston Children's Hospital, Boston, 02115, MA, USA.ORCID http://orcid.org/0000-0001-8192-8713
Steven P GygiDepartment of Cell Biology, Harvard Medical School, Boston, 02115, MA, USA.
Yoshihiko TaniJapanese Red Cross Kinki Block Blood Center, Osaka, Japan.
Manoj T DuraisinghDepartment of Immunology and Infectious Diseases, Harvard T.H. Chan School of Public Health, Boston, 02115, MA, USA. mduraisi@hsph.harvard.edu.
Harvard University · USJapanese Red Cross Society, Japan · JPBoston Children's Hospital · USNew York Blood Center · USJapanese Red Cross Fukuoka Hospital · JPStanford University · US

Funding

Identifying critical erythrocyte host factors for Plasmodium falciparum malariaDP2HL137186 · NHLBI · STANFORD UNIVERSITY · PI EGAN, ELIZABETH S. · 2016 to 2016
$2.4M
Functional analysis of red blood cell determinants of Plasmodium invasionR01HL139337 · NHLBI · HARVARD SCHOOL OF PUBLIC HEALTH · PI DURAISINGH, MANOJ T · 2017 to 2020
$2.3M
Functional analysis of erythrocyte determinants of malaria infectionR01AI091787 · NIAID · HARVARD SCHOOL OF PUBLIC HEALTH · PI DURAISINGH, MANOJ T · 2011 to 2015
$2.0M
Functional genomic analysis of host determinants of malaria infectionK08AI103034 · NIAID · STANFORD UNIVERSITY · PI EGAN, ELIZABETH S. · 2013 to 2015
$550k
NHLBI NIH HHS DP2 HL137186NHLBI NIH HHS R01 HL139337NIAID NIH HHS K08 AI103034NIAID NIH HHS R01 AI091787Wellcome Trust
6 · The paper itself

Abstract

The ATP-binding cassette transporter

Identifiers

PMID30271928
PMCPMC6123700
OpenAlexW2800881776

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.