ReviewCommunications biology2018
Beyond Royalactin and a master inducer explanation of phenotypic plasticity in honey bees.
Review in Communications biology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
17 citing papers in PubMed.
- Article
- The serotonin receptor AmFrontiers in physiology · 2026Article
- Review
- Article
- Chromatin accessibility-based characterisation of brain gene regulatory networks in three distinct honey bee polyphenisms.Nucleic acids research · 2022Article
- Single-cell transcriptomic analysis of honeybee brains identifies vitellogenin as caste differentiation-related factor.iScience · 2022Article
- Highly efficient site-specific integration of DNA fragments into the honeybee genome using CRISPR/Cas9.G3 (Bethesda, Md.) · 2022Article
- DNA Methylation in Honey Bees and the Unresolved Questions in Insect Methylomics.Advances in experimental medicine and biology · 2022Article
- Transcriptome dynamics during metamorphosis of imaginal discs into wings and thoracic dorsum in Apis mellifera castes.BMC genomics · 2021Article
- Novel structure in the nuclei of honey bee brain neurons revealed by immunostaining.Scientific reports · 2021Article
- The neuroethology of olfactory sex communication in the honeybee Apis mellifera L.Cell and tissue research · 2021Review
- Structure of native glycolipoprotein filaments in honeybee royal jelly.Nature communications · 2020Article
- Feminizer and doublesex knock-outs cause honey bees to switch sexes.PLoS biology · 2019Article
- A genetic switch for worker nutrition-mediated traits in honeybees.PLoS biology · 2019Article
- Characterization of a Dopamine Transporter and Its Splice Variant Reveals Novel Features of Dopaminergic Regulation in the Honey Bee.Frontiers in physiology · 2019Article
- Honey bee Royalactin unlocks conserved pluripotency pathway in mammals.Nature communications · 2018Article
- Phenotypically distinct female castes in honey bees are defined by alternative chromatin states during larval development.Genome research · 2018Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
1 author.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Distinct female castes produced from one genotype are the trademark of a successful evolutionary invention in eusocial insects known as reproductive division of labour. In honey bees, fertile queens develop from larvae fed a complex diet called royal jelly. Recently, one protein in royal jelly, dubbed Royalactin, was deemed to be the exclusive driver of queen bee determination. However, this notion has not been universally accepted. Here I critically evaluate this line of research and argue that the sheer complexity of creating alternate phenotypes from one genotype cannot be reduced to a single dietary component. An acceptable model of environmentally driven caste differentiation should include the facets of dynamic thinking, such as the concepts of attractor states and genetic hierarchical networks.
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.